UniProt P12314
High affinity immunoglobulin gamma Fc receptor I (P12314)
High affinity immunoglobulin gamma Fc receptor I (UniProt P12314): 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P12314
- Protein
- High affinity immunoglobulin gamma Fc receptor I
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 5 · 1 record with a druggable one
Structures
9 records of P12314 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3RJD | Crystal structure of Fc RI and its implication to high affinity immunoglobulin G binding | x-ray diffraction | A | — | — |
| 3RJD | Crystal structure of Fc ri and its implication to high affinity immunoglobulin G binding | x-ray diffraction | A | — | — |
| 4W4O | High-resolution crystal structure of Fc bound to its human receptor Fc-gamma-RI | x-ray diffraction | C | — | — |
| 4W4O | High-resolution crystal structure of Fc bound to its human receptor Fc-gamma-ri | x-ray diffraction | C | — | — |
| 4X4M | Structure of fcgammari in complex with Fc reveals the importance of glycan recognition for high… | x-ray diffraction | E, F | — | — |
| 4ZNE | IgG1 Fc-FcgammaRI ecd complex | x-ray diffraction | A | NAG, ZN | 1 (best 0.39) |
| 4ZNE | IGG1 Fc-fcgammari ecd complex | x-ray diffraction | A | — | — |
| 8DIN | The complex structure between human IgG1 Fc and its high affinity receptor FcgRI H174R variant | x-ray diffraction | C | NAG | 4 (best 0.55) |
| P12314 | AlphaFold monomer V2.0 prediction for high affinity immunoglobulin gamma Fc receptor I (P12314) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3RJD chain A against the predicted model P12314: TM-score 0.97, RMSD 1.15 Å
- 3RJD chain A against the predicted model P12314: TM-score 0.97, RMSD 1.15 Å
- 8DIN chain C against the predicted model P12314: TM-score 0.96, RMSD 1.34 Å
- 4ZNE chain A against the predicted model P12314: TM-score 0.95, RMSD 1.38 Å
- 4ZNE chain A against the predicted model P12314: TM-score 0.95, RMSD 1.38 Å
- 4X4M chain E against the predicted model P12314: TM-score 0.92, RMSD 1.91 Å
- 4W4O chain C against the predicted model P12314: TM-score 0.92, RMSD 1.82 Å
- 4W4O chain C against the predicted model P12314: TM-score 0.92, RMSD 1.82 Å
- 4X4M chain F against the predicted model P12314: TM-score 0.91, RMSD 2.08 Å
Elsewhere
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