UniProt P11607
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (P11607)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (UniProt P11607), EC 3.6.3.8: 4 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 11 pockets. Binding sites, druggability and experiment against…
- UniProt
- P11607
- Protein
- Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
- EC
- 3.6.3.8
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 11 · 1 record with a druggable one
Structures
5 records of P11607 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5MPM | SERCA2a from pig heart | x-ray diffraction | A | MGF, CZA, MG, K | 11 (best 0.84) |
| 5MPM | SERCA2A from pig heart | x-ray diffraction | A | MGF, CZA, MG, K | — |
| 6HXB | SERCA2a from pig heart | x-ray diffraction | A | CA, ACP, K | — |
| 6HXB | SERCA2A from pig heart | x-ray diffraction | A | CA, ACP, K | — |
| P11607 | AlphaFold monomer V2.0 prediction for SARCOPLASMIC/ENDOPLASMIC reticulum calcium ATPase 2 (P11607) | predicted | A | — | — |
Ligands
- K · Potassium ion · in 4 records
- ACP · Phosphomethylphosphonic acid adenylate ester · in 2 records
- CA · Calcium ion · in 2 records
- CZA · (6ar,11as,11br)-10-acetyl-9-hydroxy-7,7-dimethyl-2,6, 6A,7,11A,11B-hexahydro-11H-pyrrolo[1',2':2, 3]isoindolo[4,5,6-cd]indol-11-one · in 2 records
- MG · Magnesium ion · in 2 records
- MGF · Trifluoromagnesate · in 2 records
Experiment against prediction
- 5MPM chain A against the predicted model P11607: TM-score 0.97, RMSD 1.99 Å
- 5MPM chain A against the predicted model P11607: TM-score 0.97, RMSD 1.99 Å
- 6HXB chain A against the predicted model P11607: TM-score 0.67, RMSD 6.20 Å
- 6HXB chain A against the predicted model P11607: TM-score 0.67, RMSD 6.20 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.