UniProt P11498
Pyruvate carboxylase, mitochondrial (P11498)
Pyruvate carboxylase, mitochondrial (UniProt P11498), EC 6.4.1.1: 13 experimental structures on GenesisL1, 6 ligands bound, 140 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P11498
- Protein
- Pyruvate carboxylase, mitochondrial
- EC
- 6.4.1.1
- Experimental structures
- 13
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 140 · 7 records with a druggable one
Structures
13 records of P11498 in the MolNFT archive: 13 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3BG3 | Crystal Structure of Human Pyruvate Carboxylase (missing the biotin carboxylase domain at the… | x-ray diffraction | A, B, C, D | — | — |
| 3BG3 | Crystal structure of human pyruvate carboxylase (missing the biotin carboxylase domain at the… | x-ray diffraction | A, B, C, D | — | — |
| 3BG9 | Crystal Structure of Human Pyruvate Carboxylase (missing the biotin carboxylase domain at the… | x-ray diffraction | A, B, C, D | — | — |
| 3BG9 | Crystal structure of human pyruvate carboxylase (missing the biotin carboxylase domain at the… | x-ray diffraction | A, B, C, D | — | — |
| 7WTA | Cryo-EM structure of human pyruvate carboxylase in apo state | electron microscopy | A, B, C, D | BTI | 20 (best 0.89) |
| 7WTB | Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA | electron microscopy | A, B, C, D | BTI, ANP, ACO | 20 (best 0.84) |
| 7WTC | Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the ground state | electron microscopy | A, B, C, D | BTI, ACO | — |
| 7WTD | Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 1 | electron microscopy | A, B, C, D | ATP, COA | 20 (best 0.82) |
| 7WTE | Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 2 | electron microscopy | A, B, C, D | ATP, ACO | 20 (best 0.86) |
| 8HWL | Human Pyruvate Carboxylase | electron microscopy | A, B, C, E | BTI | 20 (best 0.81) |
| 8J7O | Human pyruvate carboxylase in BCCP-CTS state without BC | electron microscopy | A, B, C, E | BTI | 20 (best 0.81) |
| 8XL9 | Structure of human pyruvate carboxylase | electron microscopy | A, B, C, D | BTN | 20 (best 0.82) |
| P11498 | AlphaFold monomer V2.0 prediction for pyruvate carboxylase, mitochondrial (P11498) | — | — | — |
Ligands
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.