UniProt P10987
Actin-5C (P10987)
Actin-5C (UniProt P10987), EC 3.6.4.-: 27 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P10987
- Protein
- Actin-5C
- EC
- 3.6.4.-
- Experimental structures
- 27
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 20 · 1 record with a druggable one
Structures
28 records of P10987 in the MolNFT archive: 27 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2HF3 | Crystal structure of monomeric Actin in the ADP bound state | x-ray diffraction | A | — | — |
| 2HF3 | Crystal structure of monomeric actin in the ADP bound state | x-ray diffraction | A | — | — |
| 2HF4 | Crystal structure of Monomeric Actin in its ATP-bound state | x-ray diffraction | A | — | — |
| 2HF4 | Crystal structure of monomeric actin in its ATP-bound state | x-ray diffraction | A | — | — |
| 3EKS | Crystal Structure of Monomeric Actin bound to Cytochalasin D | x-ray diffraction | A | — | — |
| 3EKS | Crystal structure of monomeric actin bound to cytochalasin D | x-ray diffraction | A | — | — |
| 3EKU | Crystal Structure of Monomeric Actin bound to Cytochalasin D | x-ray diffraction | A | — | — |
| 3EKU | Crystal structure of monomeric actin bound to cytochalasin D | x-ray diffraction | A | — | — |
| 3EL2 | Crystal Structure of Monomeric Actin Bound to Ca-ATP | x-ray diffraction | A | — | — |
| 3EL2 | Crystal structure of monomeric actin bound to ca-ATP | x-ray diffraction | A | — | — |
| 3MMV | Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation | x-ray diffraction | A | — | — |
| 3MMV | Structures of actin-bound WH2 domains of spire and the implication for filament nucleation | x-ray diffraction | A | — | — |
| 3MN6 | Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation | x-ray diffraction | A, F, K | — | — |
| 3MN6 | Structures of actin-bound WH2 domains of spire and the implication for filament nucleation | x-ray diffraction | A, F, K | — | — |
| 3MN7 | Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation | x-ray diffraction | A | — | — |
| 3MN7 | Structures of actin-bound WH2 domains of spire and the implication for filament nucleation | x-ray diffraction | A | — | — |
| 3MN9 | Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation | x-ray diffraction | A | — | — |
| 3MN9 | Structures of actin-bound WH2 domains of spire and the implication for filament nucleation | x-ray diffraction | A | — | — |
| 4JHD | Crystal Structure of an Actin Dimer in Complex with the Actin Nucleator Cordon-Bleu | x-ray diffraction | A, B, D, E | — | — |
| 4JHD | Crystal structure of an actin dimer in complex with the actin nucleator cordon-bleu | x-ray diffraction | A, B, D, E | — | — |
| 4M63 | Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL | x-ray diffraction | C, D, E | — | — |
| 4M63 | Crystal structure of a filament-like actin trimer bound to the bacterial effector vopl | x-ray diffraction | C, D, E | — | — |
| 4RWT | Structure of actin-Lmod complex | x-ray diffraction | A, B | — | — |
| 4RWT | Structure of actin-lmod complex | x-ray diffraction | A, B | — | — |
| 5WFN | Revised model of leiomodin 2-mediated actin regulation (alternate refinement of PDB 4RWT) | x-ray diffraction | A, B | ANP, MG | — |
| 5WFN | Revised model of leiomodin 2-mediated actin regulation (alternate refinement of pdb 4RWT) | x-ray diffraction | A, B | ANP, MG | — |
| 8OH4 | Subtomogram averaging structure of cofilactin filament inside microtubule lumen of Drosophila S2… | electron microscopy | A, B, C, D, E, F, G, H | — | 20 (best 0.77) |
| P10987 | AlphaFold monomer V2.0 prediction for actin-5C (P10987) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4M63 chain D against the predicted model P10987: TM-score 0.99, RMSD 0.83 Å
- 4M63 chain D against the predicted model P10987: TM-score 0.99, RMSD 0.83 Å
- 3MMV chain A against the predicted model P10987: TM-score 0.98, RMSD 0.91 Å
- 3MMV chain A against the predicted model P10987: TM-score 0.98, RMSD 0.91 Å
- 3MN9 chain A against the predicted model P10987: TM-score 0.98, RMSD 0.94 Å
- 3MN9 chain A against the predicted model P10987: TM-score 0.98, RMSD 0.94 Å
- 4M63 chain C against the predicted model P10987: TM-score 0.98, RMSD 1.03 Å
- 4M63 chain C against the predicted model P10987: TM-score 0.98, RMSD 1.03 Å
- 3MN7 chain A against the predicted model P10987: TM-score 0.98, RMSD 0.98 Å
- 3MN7 chain A against the predicted model P10987: TM-score 0.98, RMSD 0.98 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.