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UniProt P0DPB6

DNA-directed RNA polymerases I and III subunit RPAC2 (P0DPB6)

DNA-directed RNA polymerases I and III subunit RPAC2 (UniProt P0DPB6): 31 experimental structures and 1 predicted model on GenesisL1, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P0DPB6
Protein
DNA-directed RNA polymerases I and III subunit RPAC2
Experimental structures
31
Predicted models
1
Pockets
23 · 15 records with a druggable one

Structures

32 records of P0DPB6 in the MolNFT archive: 31 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
7A6HCryo-EM structure of human apo RNA polymerase IIIelectron microscopyK——
7AE1Cryo-EM structure of human RNA Polymerase III elongation complex 1electron microscopyK—1 (best 0.79)
7AE1Cryo-EM structure of human RNA polymerase III elongation complex 1electron microscopyK——
7AE3Cryo-EM structure of human RNA Polymerase III elongation complex 3electron microscopyK—1 (best 0.80)
7AE3Cryo-EM structure of human RNA polymerase III elongation complex 3electron microscopyK——
7AEACryo-EM structure of human RNA Polymerase III elongation complex 2electron microscopyK—1 (best 0.82)
7AEACryo-EM structure of human RNA polymerase III elongation complex 2electron microscopyK——
7ASTApo Human RNA Polymerase IIIelectron microscopyG—1 (best 0.78)
7ASTApo human RNA polymerase IIIelectron microscopyG——
7D58cryo-EM structure of human RNA polymerase III in elongating stateelectron microscopyK—2 (best 0.89)
7D58Cryo-EM structure of human RNA polymerase III in elongating stateelectron microscopyK——
7D59cryo-EM structure of human RNA polymerase III in apo stateelectron microscopyK—1 (best 0.84)
7D59Cryo-EM structure of human RNA polymerase III in apo stateelectron microscopyK——
7DN3Structure of human RNA polymerase III elongation complexelectron microscopyK——
7DU2RNA polymerase III ec complex in post-translocation stateelectron microscopyK——
7FJIhuman Pol III elongation complexelectron microscopyK—1 (best 0.81)
7FJIHuman pol III elongation complexelectron microscopyK——
7FJJhuman Pol III pre-termination complexelectron microscopyK—1 (best 0.78)
7FJJHuman pol III pre-termination complexelectron microscopyK——
7OB9Cryo-EM structure of human RNA Polymerase I in elongation stateelectron microscopyK—2 (best 0.75)
7OB9Cryo-EM structure of human RNA polymerase I in elongation stateelectron microscopyK——
7OBACryo-EM structure of human RNA Polymerase I in complex with RRN3electron microscopyK—2 (best 0.79)
7OBACryo-EM structure of human RNA polymerase I in complex with RRN3electron microscopyK——
7OBBCryo-EM structure of human RNA Polymerase I Open Complexelectron microscopyK—3 (best 0.79)
7OBBCryo-EM structure of human RNA polymerase I open complexelectron microscopyK——
7VBAStructure of the pre state human RNA Polymerase I Elongation Complexelectron microscopyK——
7VBBStructure of the post state human RNA Polymerase I Elongation Complexelectron microscopyK—3 (best 0.79)
8A43Human RNA polymerase Ielectron microscopyK—2 (best 0.78)
8A43Human RNA polymerase Ielectron microscopyK——
8ITYhuman RNA polymerase III pre-initiation complex closed DNA 1electron microscopyK—1 (best 0.78)
8IUERNA polymerase III pre-initiation complex melting complex 1electron microscopyK—1 (best 0.77)
P0DPB6AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases I and III subunit RPAC2 (P0DPB6)predictedA——

Experiment against prediction

Elsewhere

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