UniProt P0DN34
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (P0DN34)
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (UniProt P0DN34): 31 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 17 pockets. Binding sites, druggability and experiment against…
- UniProt
- P0DN34
- Protein
- NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1
- Experimental structures
- 31
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 17 · 16 records with a druggable one
Structures
32 records of P0DN34 in the MolNFT archive: 31 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6G2J | Mouse mitochondrial complex I in the active state | electron microscopy | f | 3PE, CDL | 1 (best 0.85) |
| 6G2J | Mouse mitochondrial complex I in the active state | electron microscopy | f | 3PE, CDL | — |
| 6G72 | Mouse mitochondrial complex I in the deactive state | electron microscopy | f | — | 1 (best 0.86) |
| 6G72 | Mouse mitochondrial complex I in the deactive state | electron microscopy | f | — | — |
| 6ZR2 | Cryo-EM structure of respiratory complex I in the active state from Mus musculus at 3.1 A | electron microscopy | f | 3PE, CDL | 1 (best 0.83) |
| 6ZR2 | Cryo-EM structure of respiratory complex I in the active state from mus musculus at 3.1 a | electron microscopy | f | 3PE, CDL | — |
| 6ZTQ | Cryo-EM structure of respiratory complex I from Mus musculus inhibited by piericidin A at 3.0 A | electron microscopy | f | CDL, 3PE | 1 (best 0.84) |
| 6ZTQ | Cryo-EM structure of respiratory complex I from mus musculus inhibited by piericidin a at 3.0 a | electron microscopy | f | CDL | — |
| 7AK5 | Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2 A | electron microscopy | f | CDL, 3PE | — |
| 7AK5 | Cryo-EM structure of respiratory complex I in the deactive state from mus musculus at 3.2 a | electron microscopy | f | CDL, 3PE | — |
| 7AK6 | Cryo-EM structure of ND6-P25L mutant respiratory complex I from mus musculus at 3.8 a | electron microscopy | f | CDL | — |
| 7B93 | Cryo-EM structure of mitochondrial complex I from Mus musculus inhibited by IACS-2858 at 3.0 A | electron microscopy | f | CDL, 3PE | — |
| 7B93 | Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at 3.0 a | electron microscopy | f | CDL, 3PE | — |
| 7PSA | The acetogenin-bound complex I of Mus musculus resolved to 3.4 angstroms | electron microscopy | f | 3PE, CDL | 1 (best 0.85) |
| 8C2S | Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 1). | electron microscopy | f | CDL | — |
| 8CA3 | Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 2). | electron microscopy | f | CDL | 1 (best 0.84) |
| 8IAQ | Respiratory complex Membrane domain of CI, focused map of type I, Wild type mouse under… | electron microscopy | f | CDL | 1 (best 0.69) |
| 8IB4 | Respiratory complex CI:CIII2, type IA, Wild type mouse under cold temperature | electron microscopy | f | CDL | — |
| 8IB6 | Respiratory complex Membrane domain of CI, focus-refined of type IA, Wild type mouse under cold… | electron microscopy | f | CDL | 2 (best 0.83) |
| 8IB9 | Respiratory complex CI:CIII2, type IB, Wild type mouse under cold temperature | electron microscopy | f | 3PE, CDL | — |
| 8IBB | Respiratory complex Membrane domain of CI, focus-refined of type IB, Wild type mouse under cold… | electron microscopy | f | 3PE, CDL | 1 (best 0.74) |
| 8IBD | Respiratory complex CI:CIII2, type II, Wild type mouse under cold temperature | electron microscopy | f | CDL | — |
| 8IBF | Respiratory complex Membrane domain of CI, focus-refined of type II, Wild type mouse under cold… | electron microscopy | f | CDL | 1 (best 0.76) |
| 8IC2 | Respiratory complex CI:CIII2, type I, PERK -/- mouse under cold temperature | electron microscopy | f | CDL | — |
| 8IC4 | Respiratory complex Membrane domain of CI, focus-refined of type I, PERK -/- mouse under cold… | electron microscopy | f | CDL | 1 (best 0.71) |
| 8OM1 | Mitochondrial complex I from Mus musculus in the active state | electron microscopy | f | 3PE, CDL | 1 (best 0.87) |
| 8PW6 | C respirasome from murine liver | electron microscopy | f1 | 3PE, CDL | 1 (best 0.84) |
| 8PW7 | A respirasome from murine liver | electron microscopy | f1 | 3PE, CDL | — |
| 8RGP | Closed Complex I from murine brain | electron microscopy | f | CDL, 3PE | 1 (best 0.84) |
| 8RGQ | Open Complex I from murine liver | electron microscopy | f | 3PE, CDL | 1 (best 0.86) |
| 8RGR | Closed Complex I from murine liver | electron microscopy | f | 3PE, CDL | 1 (best 0.87) |
| P0DN34 | AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1… | predicted | A | — | — |
Ligands
Experiment against prediction
- 6ZTQ chain f against the predicted model P0DN34: TM-score 0.91, RMSD 0.83 Å
- 6ZTQ chain f against the predicted model P0DN34: TM-score 0.91, RMSD 0.83 Å
- 8CA3 chain f against the predicted model P0DN34: TM-score 0.91, RMSD 0.80 Å
- 8IC2 chain f against the predicted model P0DN34: TM-score 0.90, RMSD 1.03 Å
- 8IC4 chain f against the predicted model P0DN34: TM-score 0.90, RMSD 1.03 Å
- 6ZR2 chain f against the predicted model P0DN34: TM-score 0.90, RMSD 0.88 Å
- 6ZR2 chain f against the predicted model P0DN34: TM-score 0.90, RMSD 0.88 Å
- 8OM1 chain f against the predicted model P0DN34: TM-score 0.90, RMSD 1.06 Å
- 7B93 chain f against the predicted model P0DN34: TM-score 0.90, RMSD 0.91 Å
- 7B93 chain f against the predicted model P0DN34: TM-score 0.90, RMSD 0.91 Å
Elsewhere
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