UniProt P0CR36
3-ketodihydrosphingosine reductase TSC10 (P0CR36)
3-ketodihydrosphingosine reductase TSC10 (UniProt P0CR36), EC 1.1.1.102: 1 experimental structure and 1 predicted model on GenesisL1, 1 ligand bound, 5 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P0CR36
- Protein
- 3-ketodihydrosphingosine reductase TSC10
- EC
- 1.1.1.102
- Experimental structures
- 1
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 5 · 2 records with a druggable one
Structures
2 records of P0CR36 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8JAT | Crystal structure of the 3-ketodihydrosphingosine reductase TSC10 from Cryptococcus neoformans | x-ray diffraction | A | NDP | 1 (best 0.56) |
| P0CR36 | AlphaFold monomer V2.0 prediction for 3-ketodihydrosphingosine reductase TSC10 (P0CR36) | predicted | A | — | 4 (best 0.77) |
Ligands
- NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate · in 1 record
Experiment against prediction
- 8JAT chain A against the predicted model P0CR36: TM-score 0.98, RMSD 0.67 Å
Elsewhere
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