MolNFT v1 · #480831 · protein
AlphaFold monomer V2.0 prediction for 3-ketodihydrosphingosine reductase TSC10 (P0CR36)
P0CR36: “AlphaFold monomer V2.0 prediction for 3-ketodihydrosphingosine reductase TSC10 (P0CR36)”. 4 pockets (best druggability 0.77). MolNFT v1 #480831 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P0CR36
- Type
- protein
- Length
- 335 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x71112d4fF7ebb3b617963c05f052289e073082FD
- Molecule
- 3-ketodihydrosphingosine reductase TSC10
- UniProt
- P0CR36
- Pockets
- 4 · best druggability 0.77
Structure
1 distinct chain · 57% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-ketodihydrosphingosine reductase TSC10 | protein | 335 | 57% helix, 11% strand | P0CR36 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 628 | 0.77 | 0.83 | 73 | empty |
| 2 | 201 | 0.58 | 0.81 | 22 | empty |
| 3 | 70 | 0.35 | 0.77 | 18 | empty |
| 4 | 71 | 0.30 | 0.73 | 15 | empty |
Compared structures
- 8JAT · Crystal structure of the 3-ketodihydrosphingosine reductase TSC10 from Cryptococcus… · an experimental structure of the same protein · chain A against A, TM-score 0.60
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0CR36
- Elsewhere: UniProt P0CR36 · AlphaFold DB P0CR36
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