UniProt P0CL62
Probable endoribonuclease MazF7 (P0CL62)
Probable endoribonuclease MazF7 (UniProt P0CL62), EC 3.1.-.-: 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P0CL62
- Protein
- Probable endoribonuclease MazF7
- EC
- 3.1.-.-
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
6 records of P0CL62 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5WYG | The crystal structure of the apo form of mtb mazf | x-ray diffraction | A, C | — | — |
| 6A6X | The crystal structure of the Mtb MazE-MazF-mt9 complex | x-ray diffraction | A, B | SO4 | 2 (best 0.54) |
| 6A6X | The crystal structure of the mtb maze-mazf-MT9 complex | x-ray diffraction | A, B | SO4 | — |
| 7DU4 | The structure of the M.tb MazF-mt9 toxin in complex with a fragment of cognate antitoxin | x-ray diffraction | A, B | — | 1 (best 0.46) |
| 7DU4 | The structure of the M.TB mazf-MT9 toxin in complex with a fragment of cognate antitoxin | x-ray diffraction | A, B | — | — |
| P0CL62 | AlphaFold monomer V2.0 prediction for probable endoribonuclease MAZF7 (P0CL62) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 7DU4 chain A against the predicted model P0CL62: TM-score 0.98, RMSD 0.51 Å
- 7DU4 chain A against the predicted model P0CL62: TM-score 0.98, RMSD 0.51 Å
- 5WYG chain C against the predicted model P0CL62: TM-score 0.98, RMSD 0.57 Å
- 5WYG chain A against the predicted model P0CL62: TM-score 0.98, RMSD 0.78 Å
- 7DU4 chain B against the predicted model P0CL62: TM-score 0.97, RMSD 0.87 Å
- 6A6X chain B against the predicted model P0CL62: TM-score 0.95, RMSD 0.90 Å
- 6A6X chain B against the predicted model P0CL62: TM-score 0.95, RMSD 0.90 Å
- 6A6X chain A against the predicted model P0CL62: TM-score 0.93, RMSD 0.99 Å
- 6A6X chain A against the predicted model P0CL62: TM-score 0.93, RMSD 0.99 Å
Elsewhere
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