UniProt P0C581
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (P0C581)
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (UniProt P0C581): 8 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0C581
- Protein
- PAN2-PAN3 deadenylation complex catalytic subunit PAN2
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 13 · 1 record with a druggable one
Structures
9 records of P0C581 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4CZV | Structure of the Neurospora crassa Pan2 WD40 domain | x-ray diffraction | A, B | — | — |
| 4CZV | Structure of the neurospora crassa PAN2 WD40 domain | x-ray diffraction | A, B | — | — |
| 4CZW | Structure of the Neurospora crassa Pan2 catalytic unit (protease and nuclease domain) | x-ray diffraction | A | — | — |
| 4CZW | Structure of the neurospora crassa PAN2 catalytic unit (protease and nuclease domain) | x-ray diffraction | A | — | — |
| 4CZX | Complex of Neurospora crassa PAN2 (WD40) with PAN3 (C-TERM) | x-ray diffraction | A | — | — |
| 4CZX | Complex of neurospora crassa PAN2 (WD40) with PAN3 (C-term) | x-ray diffraction | A | — | — |
| 4CZY | Complex of Neurospora crassa PAN2 (WD40-CS1) with PAN3 (pseudokinase and C-term) | x-ray diffraction | A, C | — | — |
| 4CZY | Complex of neurospora crassa PAN2 (WD40-CS1) with PAN3 (pseudokinase and C-term) | x-ray diffraction | A, C | — | — |
| P0C581 | AlphaFold monomer V2.0 prediction for PAN2-PAN3 deadenylation complex catalytic subunit PAN2… | predicted | A | — | 13 (best 0.82) |
Experiment against prediction
- 4CZW chain A against the predicted model P0C581: TM-score 0.99, RMSD 0.72 Å
- 4CZW chain A against the predicted model P0C581: TM-score 0.99, RMSD 0.72 Å
- 4CZY chain A against the predicted model P0C581: TM-score 0.95, RMSD 1.73 Å
- 4CZY chain A against the predicted model P0C581: TM-score 0.95, RMSD 1.73 Å
- 4CZX chain A against the predicted model P0C581: TM-score 0.95, RMSD 1.85 Å
- 4CZX chain A against the predicted model P0C581: TM-score 0.95, RMSD 1.85 Å
- 4CZV chain A against the predicted model P0C581: TM-score 0.95, RMSD 1.62 Å
- 4CZV chain A against the predicted model P0C581: TM-score 0.95, RMSD 1.62 Å
Elsewhere
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