UniProt P0C2H8
60S ribosomal protein L31-A (P0C2H8)
60S ribosomal protein L31-A (UniProt P0C2H8): 168 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 51 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0C2H8
- Protein
- 60S ribosomal protein L31-A
- Experimental structures
- 168
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 51 · 39 records with a druggable one
Structures
169 records of P0C2H8 in the MolNFT archive: 168 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2WW9 | Cryo-EM structure of the active yeast Ssh1 complex bound to the yeast 80S ribosome | electron microscopy | M | — | — |
| 2WW9 | Cryo-EM structure of the active yeast SSH1 complex bound to the yeast 80S ribosome | electron microscopy | M | — | — |
| 2WWA | Cryo-EM structure of idle yeast Ssh1 complex bound to the yeast 80S ribosome | electron microscopy | M | — | — |
| 2WWA | Cryo-EM structure of idle yeast SSH1 complex bound to the yeast 80S ribosome | electron microscopy | M | — | — |
| 3J6X | S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II) | electron microscopy | 71 | — | — |
| 3J6Y | S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I) | electron microscopy | 71 | — | — |
| 3J77 | Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class… | electron microscopy | 81 | — | — |
| 3J78 | Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class… | electron microscopy | 81 | — | — |
| 3JCT | Cryo-em structure of eukaryotic pre-60S ribosomal subunits | electron microscopy | d | — | — |
| 4U3M | Crystal structure of Anisomycin bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4U3N | Crystal structure of CCA trinucleotide bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4U3U | Crystal structure of Cycloheximide bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4U4N | Crystal structure of Edeine bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4U4O | Crystal structure of Geneticin bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4U4Q | Crystal structure of Homoharringtonine bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4U4R | Crystal structure of Lactimidomycin bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4U4U | Crystal structure of Lycorine bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4U4Y | Crystal structure of Pactamycin bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4U4Z | Crystal structure of Phyllanthoside bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4U50 | Crystal structure of Verrucarin bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4U51 | Crystal structure of Narciclasine bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4U52 | Crystal structure of Nagilactone C bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4U53 | Crystal structure of Deoxynivalenol bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4U55 | Crystal structure of Cryptopleurine bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4U56 | Crystal structure of Blasticidin S bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4U6F | Crystal structure of T-2 toxin bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | — | — |
| 4V6I | Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces… | electron microscopy | Bg | — | — |
| 4V7F | Arx1 pre-60S particle. | electron microscopy | c | — | — |
| 4V7F | ARX1 pre-60S particle. | electron microscopy | c | — | — |
| 4V7R | Yeast 80S ribosome. | x-ray diffraction | Ba, Da | — | — |
| 4V88 | The structure of the eukaryotic ribosome at 3.0 A resolution. | x-ray diffraction | Bd, Dd | — | — |
| 4V8T | Cryo-EM Structure of the 60S Ribosomal Subunit in Complex with Arx1 and Rei1 | electron microscopy | d | — | — |
| 4V8Y | Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex | electron microscopy | Bd | — | — |
| 4V8Z | Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex | electron microscopy | Bd | — | — |
| 5DGF | Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA… | x-ray diffraction | O1, o1 | — | — |
| 5DGV | Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA… | x-ray diffraction | O1, o1 | — | — |
| 5FCI | Structure of the vacant uL3 W255C mutant 80S yeast ribosome | x-ray diffraction | O1, o1 | OHX, MG | — |
| 5GAK | Yeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5A | electron microscopy | f | — | 1 (best 0.88) |
| 5H4P | Structural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1 | electron microscopy | d | — | — |
| 5I4L | Crystal structure of Amicoumacin A bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | OHX, MG | — |
| 5JCS | Cryo-EM structure of the RIX1-REA1 pre-60S particle | electron microscopy | d | — | 1 (best 0.84) |
| 5JUO | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | IA | — | 2 (best 0.88) |
| 5JUP | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | IA | — | — |
| 5JUS | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | IA | — | — |
| 5JUT | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | IA | — | 1 (best 0.88) |
| 5JUU | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | IA | — | — |
| 5LYB | Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA… | x-ray diffraction | O1, o1 | MG, OHX | 1 (best 0.86) |
| 5M1J | Nonstop ribosomal complex bound with Dom34 and Hbs1 | electron microscopy | d5 | MG | 1 (best 0.87) |
| 5MC6 | Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae | electron microscopy | BC | — | — |
| 5MEI | Crystal structure of Agelastatin A bound to the 80S ribosome | x-ray diffraction | AE, DF | OHX, MG | — |
| 5NDG | Crystal structure of geneticin (G418) bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | MG | — |
| 5NDV | Crystal structure of Paromomycin bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | MG | 1 (best 0.88) |
| 5NDW | Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosome | x-ray diffraction | o1, O1 | MG | 1 (best 0.88) |
| 5OBM | Crystal structure of Gentamicin bound to the yeast 80S ribosome | x-ray diffraction | O1, o1 | MG | — |
| 5T62 | Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome… | electron microscopy | q | — | — |
| 5T6R | Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome… | electron microscopy | q | — | — |
| 5TGA | Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA… | x-ray diffraction | O1, o1 | OHX, MG | — |
| 5TGM | Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA… | x-ray diffraction | O1, o1 | OHX, MG | — |
| 6ELZ | State E (TAP-Flag-Ytm1 E80A) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | electron microscopy | d | — | 2 (best 0.85) |
| 6EM5 | State D architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar… | electron microscopy | d | — | 1 (best 0.70) |
109 records more on the page itself.
Ligands
Experiment against prediction
- 7UQB chain d against the predicted model P0C2H8: TM-score 0.99, RMSD 0.43 Å
- 8P8N chain RD against the predicted model P0C2H8: TM-score 0.99, RMSD 0.43 Å
- 8P8U chain RD against the predicted model P0C2H8: TM-score 0.99, RMSD 0.44 Å
- 8PFR chain RD against the predicted model P0C2H8: TM-score 0.99, RMSD 0.43 Å
- 7UOO chain d against the predicted model P0C2H8: TM-score 0.99, RMSD 0.46 Å
- 7UQZ chain d against the predicted model P0C2H8: TM-score 0.99, RMSD 0.47 Å
- 8P8M chain RD against the predicted model P0C2H8: TM-score 0.99, RMSD 0.44 Å
- 8BN3 chain O1 against the predicted model P0C2H8: TM-score 0.98, RMSD 0.71 Å
- 6YLG chain d against the predicted model P0C2H8: TM-score 0.98, RMSD 0.60 Å
- 7UG6 chain d against the predicted model P0C2H8: TM-score 0.98, RMSD 0.68 Å
Elsewhere
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