UniProt P0AFC1
Dihydroneopterin triphosphate diphosphatase (P0AFC1)
Dihydroneopterin triphosphate diphosphatase (UniProt P0AFC1), EC 3.6.1.67: 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P0AFC1
- Protein
- Dihydroneopterin triphosphate diphosphatase
- EC
- 3.6.1.67
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 3 · 3 records with a druggable one
Structures
7 records of P0AFC1 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5U7E | Apo dihydroneopterin triphosphate pyrophosphohydrolase from E. coli | x-ray diffraction | A | SO4 | — |
| 5U7E | Apo dihydroneopterin triphosphate pyrophosphohydrolase from E. COLI | x-ray diffraction | A | SO4 | — |
| 5U7F | Co-bound dihydroneopterin triphosphate pyrophosphohydrolase from E. coli | x-ray diffraction | A | SO4, CO | 1 (best 0.75) |
| 5U7F | Co-bound dihydroneopterin triphosphate pyrophosphohydrolase from E. COLI | x-ray diffraction | A | SO4, CO | — |
| 5U7H | Ni-bound dihydroneopterin triphosphate pyrophosphohydrolase from E. coli | x-ray diffraction | A | SO4, NI | 1 (best 0.71) |
| 5U7H | Ni-bound dihydroneopterin triphosphate pyrophosphohydrolase from E. COLI | x-ray diffraction | A | SO4, NI | — |
| P0AFC1 | AlphaFold monomer V2.0 prediction for dihydroneopterin triphosphate diphosphatase (P0AFC1) | predicted | A | — | 1 (best 0.69) |
Ligands
Experiment against prediction
- 5U7F chain A against the predicted model P0AFC1: TM-score 0.99, RMSD 0.44 Å
- 5U7F chain A against the predicted model P0AFC1: TM-score 0.99, RMSD 0.44 Å
- 5U7H chain A against the predicted model P0AFC1: TM-score 0.99, RMSD 0.45 Å
- 5U7H chain A against the predicted model P0AFC1: TM-score 0.99, RMSD 0.45 Å
- 5U7E chain A against the predicted model P0AFC1: TM-score 0.99, RMSD 0.49 Å
- 5U7E chain A against the predicted model P0AFC1: TM-score 0.99, RMSD 0.49 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.