UniProt P0ACE0
Hydrogenase-2 large chain (P0ACE0)
Hydrogenase-2 large chain (UniProt P0ACE0), EC 1.12.99.6: 11 experimental structures on GenesisL1, 8 ligands bound, 22 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P0ACE0
- Protein
- Hydrogenase-2 large chain
- EC
- 1.12.99.6
- Experimental structures
- 11
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 22 · 2 records with a druggable one
Structures
11 records of P0ACE0 in the MolNFT archive: 11 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6EHQ | E. COLI hydrogenase-2 (as isolated form). | x-ray diffraction | L, M | F3S, SF4, FCO, NI, MG | — |
| 6EHS | E. coli Hydrogenase-2 chemically reduced structure | x-ray diffraction | L, M | F3S, SF4, FCO, NI, MG, DTN | — |
| 6EHS | E. COLI hydrogenase-2 chemically reduced structure | x-ray diffraction | L, M | F3S, SF4, FCO, NI, MG, DTN | — |
| 6EN9 | E. coli Hydrogenase-2 (hydrogen reduced form) | x-ray diffraction | L, M | F3S, SF4, FCO, NI, MG | 11 (best 0.83) |
| 6EN9 | E. COLI hydrogenase-2 (hydrogen reduced form) | x-ray diffraction | L, M | F3S, SF4, FCO, NI, MG | — |
| 6G7M | Four-site variant (Y222C, C197S, C432S, C433S) of E. coli hydrogenase-2 | x-ray diffraction | L, M | F3S, SF4, FCO, NI, MG | 11 (best 0.81) |
| 6G7M | Four-site variant (Y222C, C197S, C432S, C433S) of E. COLI hydrogenase- 2 | x-ray diffraction | L, M | F3S, SF4, FCO, NI, MG | — |
| 6GAM | Structure of E14Q variant of E. COLI hydrogenase-2 (as-isolated enzyme) | x-ray diffraction | L, M | F3S, SF4, FCO, NI, MG | — |
| 6GAN | Structure of fully reduced hydrogenase (hyd-2) variant E14Q | x-ray diffraction | L, M | F3S, SF4, FCO, NI, MG | — |
| 7NEM | Hydrogenase-2 variant R479K - anaerobically oxidised form | x-ray diffraction | L, M | F3S, SF4, FCO, NI, MG, OXY | — |
| P0ACE0 | AlphaFold monomer V2.0 prediction for hydrogenase-2 large chain (P0ACE0) | — | — | — |
Ligands
Elsewhere
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