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UniProt P0A6M8

Elongation factor G (P0A6M8)

Elongation factor G (UniProt P0A6M8): 14 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P0A6M8
Protein
Elongation factor G
Experimental structures
14
Predicted models
1
Ligands
4

Structures

15 records of P0A6M8 in the MolNFT archive: 14 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
2RDO50S subunit with EF-G(GDPNP) and RRF boundelectron microscopy7——
2RDO50S subunit with ef-G(GDPNP) and rrf boundelectron microscopy7——
3J0EModels for the T. thermophilus ribosome recycling factor and the E. coli elongation factor G bound…electron microscopyH——
3J0EModels for the T. thermophilus ribosome recycling factor and the E. COLI elongation factor G bound…electron microscopyH——
3J9ZActivation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor Gelectron microscopyS1——
3JA1Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor Gelectron microscopyS3——
4V7BVisualization of two tRNAs trapped in transit during EF-G-mediated translocationelectron microscopyAY——
4V7DStructure of the Ribosome with Elongation Factor G Trapped in the Pre-Translocation State…electron microscopyBZ——
4V9OControl of ribosomal subunit rotation by elongation factor Gx-ray diffractionBV, DV, FV, HV——
4V9PControl of ribosomal subunit rotation by elongation factor Gx-ray diffractionBV, DV, FV, HV——
7N2CElongating 70S ribosome complex in a fusidic acid-stalled intermediate state of translocation bound…electron microscopyEFMG, FUA, GDP—
7PJVStructure of the 70S-EF-G-GDP-Pi ribosome complex with tRNAs in hybrid state 1 (H1-EF-G-GDP-Pi)electron microscopyxMG, GDP, PO4—
7PJYStructure of the 70S-EF-G-GDP ribosome complex with tRNAs in chimeric state 1 (CHI1-EF-G-GDP)electron microscopyxGDP—
7UG770S ribosome complex in an intermediate state of translocation bound to EF-G(GDP) stalled by…electron microscopyEFMG, GDP—
P0A6M8AlphaFold monomer V2.0 prediction for elongation factor G (P0A6M8)predictedA——

Ligands

  • GDP · Guanosine-5'-diphosphate · in 4 records
  • MG · Magnesium ion · in 3 records
  • FUA · Fusidic acid · in 1 record
  • PO4 · Phosphate ion · in 1 record

Experiment against prediction

Elsewhere

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