UniProt P09914
P09914
P09914 (UniProt P09914): 10 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P09914
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 4
Structures
11 records of P09914 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4HOU | Crystal Structure of N-terminal Human IFIT1 | x-ray diffraction | A, B | — | — |
| 4HOU | Crystal structure of N-terminal human IFIT1 | x-ray diffraction | A, B | — | — |
| 5UDI | IFIT1 monomeric mutant (L457E/L464E) with M7GPPP-aaaa (syn and anti conformations of cap) | x-ray diffraction | A | GTA, CA | — |
| 5UDJ | IFIT1 monomeric mutant (L457E/L464E) with gppp-aaaa | x-ray diffraction | A | G3A, CA | — |
| 5UDK | IFIT1 monomeric mutant (L457E/L464E) with PPP-AAAA | x-ray diffraction | A | CA | — |
| 5UDK | IFIT1 monomeric mutant (L457E/L464E) with ppp-aaaa | x-ray diffraction | A | CA | — |
| 5UDL | IFIT1 N216A monomeric mutant (L457E/L464E) with M7GPPP-aaaa (anti conformation of cap) | x-ray diffraction | A | GTA, CA | — |
| 5W5H | Human IFIT1 dimer with M7GPPP-aaaa | x-ray diffraction | A, C | GTA | — |
| 5W5I | Human IFIT1 dimer with ppp-aaaa | x-ray diffraction | A, C | — | — |
| 6C6K | Structural basis for preferential recognition of cap 0 RNA by a human IFIT1-IFIT3 protein complex | x-ray diffraction | A, B | MG | — |
| P09914 | AlphaFold monomer V2.0 prediction for interferon-induced protein with tetratricopeptide repeats 1… | predicted | A | — | — |
Ligands
Experiment against prediction
- 5UDI chain A against the predicted model P09914: TM-score 1.00, RMSD 0.50 Å
- 5UDL chain A against the predicted model P09914: TM-score 1.00, RMSD 0.51 Å
- 5UDK chain A against the predicted model P09914: TM-score 0.99, RMSD 0.58 Å
- 5UDK chain A against the predicted model P09914: TM-score 0.99, RMSD 0.58 Å
- 5UDJ chain A against the predicted model P09914: TM-score 0.99, RMSD 0.60 Å
- 5W5H chain C against the predicted model P09914: TM-score 0.99, RMSD 0.78 Å
- 6C6K chain B against the predicted model P09914: TM-score 0.99, RMSD 0.80 Å
- 5W5I chain A against the predicted model P09914: TM-score 0.99, RMSD 0.79 Å
- 6C6K chain A against the predicted model P09914: TM-score 0.99, RMSD 0.86 Å
- 5W5H chain A against the predicted model P09914: TM-score 0.99, RMSD 0.95 Å
Elsewhere
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