UniProt P08700
Interleukin-3 (P08700)
Interleukin-3 (UniProt P08700): 8 experimental structures and 1 predicted model on GenesisL1, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P08700
- Protein
- Interleukin-3
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 22 · 3 records with a druggable one
Structures
9 records of P08700 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1JLI | Human interleukin 3 (il-3) mutant with truncation at both N-and C-termini and 14 residue changes… | solution nmr | A | — | — |
| 1JLI | Human interleukin 3 (il-3) mutant with truncation at both N-and C- termini and 14 residue changes… | solution nmr | A | — | — |
| 5UV8 | Interleukin-3 Receptor Complex | x-ray diffraction | B, I | — | 9 (best 0.70) |
| 5UV8 | Interleukin-3 receptor complex | x-ray diffraction | B, I | — | — |
| 5UWC | Cytokine-receptor complex | x-ray diffraction | I | — | 3 (best 0.65) |
| 5UWC | Cytokine-receptor complex | x-ray diffraction | I | — | — |
| 6NMY | A Cytokine-receptor complex | x-ray diffraction | I, J | — | 10 (best 0.79) |
| 6NMY | A cytokine-receptor complex | x-ray diffraction | I, J | — | — |
| P08700 | AlphaFold monomer V2.0 prediction for interleukin-3 (P08700) | predicted | A | — | — |
Experiment against prediction
- 5UV8 chain B against the predicted model P08700: TM-score 0.95, RMSD 1.11 Å
- 5UV8 chain B against the predicted model P08700: TM-score 0.95, RMSD 1.11 Å
- 5UV8 chain I against the predicted model P08700: TM-score 0.94, RMSD 1.28 Å
- 5UV8 chain I against the predicted model P08700: TM-score 0.94, RMSD 1.28 Å
- 5UWC chain I against the predicted model P08700: TM-score 0.93, RMSD 1.52 Å
- 5UWC chain I against the predicted model P08700: TM-score 0.93, RMSD 1.52 Å
- 6NMY chain J against the predicted model P08700: TM-score 0.93, RMSD 1.17 Å
- 6NMY chain I against the predicted model P08700: TM-score 0.93, RMSD 1.20 Å
- 6NMY chain I against the predicted model P08700: TM-score 0.93, RMSD 1.20 Å
- 1JLI chain A against the predicted model P08700: TM-score 0.79, RMSD 2.16 Å
Elsewhere
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