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MolNFT v1 · #136508 · protein

Interleukin-3 receptor complex

5UV8: “Interleukin-3 receptor complex”. X-ray diffraction, 3 ligands (NAG, BMA, FUC). MolNFT v1 #136508 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5UV8
Type
protein
Length
737 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P26951, P08700
Ligands
NAG, BMA, FUC

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein259—P26951
B—protein105—P08700
G—protein265—P26951
I—protein108—P08700

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 9 copies · chains A, G
  • BMA · beta-D-mannopyranose · sugar · 3 copies
  • FUC · alpha-L-fucopyranose · sugar · 2 copies · chains A, G
  • GOL · Glycerol · additive · 3 copies · chains G

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 5UV8 · Interleukin-3 Receptor Complex · the same entry in another collection · chain I against I, TM-score 1.00
  • P26951 · AlphaFold monomer V2.0 prediction for interleukin-3 receptor subunit alpha (P26951) · a predicted model of the same protein · chain G against A, TM-score 0.97
  • P08700 · AlphaFold monomer V2.0 prediction for interleukin-3 (P08700) · a predicted model of the same protein · chain B against A, TM-score 0.95

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