UniProt P08487
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (P08487)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (UniProt P08487), EC 3.1.4.11: 15 experimental structures on GenesisL1, 7 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P08487
- Protein
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
- EC
- 3.1.4.11
- Experimental structures
- 15
- Predicted models
- 0
- Pockets
- 7 · 2 records with a druggable one
Structures
15 records of P08487 in the MolNFT archive: 15 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2FCI | Structural basis for the requirement of two phosphotyrosines in signaling mediated by Syk tyrosine… | solution nmr | A | — | — |
| 2FCI | Structural basis for the requirement of two phosphotyrosines in signaling mediated by syk tyrosine… | solution nmr | A | — | — |
| 2PLD | Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-GAMMA1 complexed with a… | solution nmr | A | — | — |
| 2PLD | Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-GAMMA1 complexed with a… | solution nmr | A | — | — |
| 2PLE | Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-GAMMA1 complexed with a… | solution nmr | A | — | — |
| 2PLE | Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-GAMMA1 complexed with a… | solution nmr | A | — | — |
| 5TNW | Phospholipase C gamma-1 C-terminal SH2 domain | x-ray diffraction | A, B | — | 1 (best 0.53) |
| 5TNW | Phospholipase C gamma-1 C-terminal SH2 domain | x-ray diffraction | A, B | — | — |
| 5TO4 | Phospholipase C gamma-1 C-terminal SH2 domain, spacegroup P212121 | x-ray diffraction | A | — | — |
| 5TO4 | Phospholipase C gamma-1 C-terminal SH2 domain, spacegroup P212121 | x-ray diffraction | A | — | — |
| 5TQ1 | Phospholipase C gamma-1 C-terminal SH2 domain bound to a phosphopeptide derived from the insulin… | x-ray diffraction | A | — | — |
| 5TQ1 | Phospholipase C gamma-1 C-terminal SH2 domain bound to a phosphopeptide derived from the insulin… | x-ray diffraction | A | — | — |
| 5TQS | Phospholipase C gamma-1 C-terminal SH2 domain bound to a phosphopeptide derived from the receptor… | x-ray diffraction | A, B, C, D | — | 6 (best 0.55) |
| 5TQS | Phospholipase C gamma-1 C-terminal SH2 domain bound to a phosphopeptide derived from the receptor… | x-ray diffraction | A, B, C, D | — | — |
| P08487 | AlphaFold monomer V2.0 prediction for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase… | — | — | — |
Elsewhere
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