UniProt P08067
Cytochrome b-c1 complex subunit Rieske, mitochondrial (P08067)
Cytochrome b-c1 complex subunit Rieske, mitochondrial (UniProt P08067), EC 7.1.1.8: 26 experimental structures and 1 predicted model on GenesisL1, 9 ligands bound, 25 pockets. Binding sites, druggability and experiment against…
- UniProt
- P08067
- Protein
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- EC
- 7.1.1.8
- Experimental structures
- 26
- Predicted models
- 1
- Ligands
- 9
- Pockets
- 25 · 6 records with a druggable one
Structures
27 records of P08067 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1KB9 | Yeast cytochrome BC1 complex | x-ray diffraction | E | — | — |
| 1KB9 | Yeast cytochrome BC1 complex | x-ray diffraction | E | — | — |
| 1KYO | Yeast cytochrome BC1 complex with bound substrate cytochrome C | x-ray diffraction | E, P | — | — |
| 1KYO | Yeast cytochrome BC1 complex with bound substrate cytochrome C | x-ray diffraction | E, P | — | — |
| 1P84 | HDBT inhibited Yeast Cytochrome bc1 Complex | x-ray diffraction | E | — | — |
| 1P84 | Hdbt inhibited yeast cytochrome BC1 complex | x-ray diffraction | E | — | — |
| 2IBZ | Yeast Cytochrome BC1 Complex with Stigmatellin | x-ray diffraction | E | — | — |
| 2IBZ | Yeast cytochrome BC1 complex with stigmatellin | x-ray diffraction | E | — | — |
| 3CX5 | Structure of complex III with bound cytochrome c in reduced state and definition of a minimal core… | x-ray diffraction | E, P | — | — |
| 3CX5 | Structure of complex III with bound cytochrome C in reduced state and definition of a minimal core… | x-ray diffraction | E, P | — | — |
| 3CXH | Structure of yeast complex III with isoform-2 cytochrome c bound and definition of a minimal core… | x-ray diffraction | E, P | — | — |
| 3CXH | Structure of yeast complex III with isoform-2 cytochrome C bound and definition of a minimal core… | x-ray diffraction | E, P | — | — |
| 4PD4 | Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of… | x-ray diffraction | E | — | — |
| 4PD4 | Structural analysis of atovaquone-inhibited cytochrome BC1 complex reveals the molecular basis of… | x-ray diffraction | E | — | — |
| 6GIQ | Saccharomyces cerevisiae respiratory supercomplex III2IV | electron microscopy | E, P | 6PH, 7PH, FES, PCF | — |
| 6HU9 | III2-IV2 mitochondrial respiratory supercomplex from S. cerevisiae | electron microscopy | E, P | PEF, FES, CDL, PCF | — |
| 6HU9 | III2-IV2 mitochondrial respiratory supercomplex from S. cerevisiae | electron microscopy | E, P | PEF, FES, CDL, PCF | — |
| 6T0B | The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae | electron microscopy | E, P | PEF, CDL, FES, PCF | 4 (best 0.79) |
| 6T0B | The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae | electron microscopy | E, P | PEF, CDL, FES, PCF | — |
| 6T15 | The III2-IV(5B)1 respiratory supercomplex from S. cerevisiae | electron microscopy | E, P | PEF, FES, PCF, CDL | 6 (best 0.80) |
| 6T15 | The III2-IV(5B)1 respiratory supercomplex from S. cerevisiae | electron microscopy | E, P | PEF, FES, PCF, CDL | — |
| 6YMX | CIII2/CIV respiratory supercomplex from Saccharomyces cerevisiae | electron microscopy | E, P | CN3, 6PH, 7PH, FES, PCF, UQ6 | 7 (best 0.80) |
| 6YMX | CIII2/CIV respiratory supercomplex from saccharomyces cerevisiae | electron microscopy | E, P | 6PH, 7PH, FES, PCF | — |
| 8E7S | III2IV2 respiratory supercomplex from Saccharomyces cerevisiae with 4 bound UQ6 | electron microscopy | C, c | PEF, FES, CDL, PCF, UQ6 | 2 (best 0.80) |
| 8EC0 | III2IV respiratory supercomplex from Saccharomyces cerevisiae cardiolipin-lacking mutant | electron microscopy | C, c | FES, PGT, PEF, PCF | 4 (best 0.87) |
| 9ETZ | III2IV respiratory supercomplex from Saccharomyces cerevisiae | electron microscopy | E, P | PEF, UQ6, FES, CDL, PCF | 2 (best 0.77) |
| P08067 | AlphaFold monomer V2.0 prediction for cytochrome B-C1 complex subunit rieske, mitochondrial (P08067) | predicted | A | — | — |
Ligands
- FES · Fe2/s2 (inorganic) cluster · in 12 records
- PCF · 1,2-diacyl-sn-glycero-3-phoshocholine · in 12 records
- PEF · Di-palmitoyl-3-sn-phosphatidylethanolamine · in 9 records
- CDL · Cardiolipin · in 8 records
- 6PH · (1R)-2-(phosphonooxy)-1-[(tridecanoyloxy)methyl]ethyl pentadecanoate · in 3 records
- 7PH · (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate · in 3 records
- UQ6 · 5-(3,7,11,15,19,23-hexamethyl-tetracosa-2,6,10,14,18, 22-hexaenyl)-2,3-dimethoxy-6-methyl-benzene-1,4-diol · in 3 records
- CN3 · (2R,5S,11R,14R)-5,8,11-trihydroxy-2-(nonanoyloxy)-5,11-dioxido-16-oxo-14-[(propanoyloxy)methyl]-4,6,10,12,15-pentaoxa-5,11-diphosphanonadec-1-yl undecanoate · in 1 record
- PGT · (1S)-2-{[{[(2R)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate · in 1 record
Experiment against prediction
- 6YMX chain E against the predicted model P08067: TM-score 0.84, RMSD 2.40 Å
- 6YMX chain E against the predicted model P08067: TM-score 0.84, RMSD 2.40 Å
- 6HU9 chain E against the predicted model P08067: TM-score 0.82, RMSD 2.56 Å
- 6HU9 chain E against the predicted model P08067: TM-score 0.82, RMSD 2.56 Å
- 6GIQ chain E against the predicted model P08067: TM-score 0.82, RMSD 2.59 Å
- 6T0B chain E against the predicted model P08067: TM-score 0.81, RMSD 2.67 Å
- 6T0B chain E against the predicted model P08067: TM-score 0.81, RMSD 2.67 Å
- 6YMX chain P against the predicted model P08067: TM-score 0.80, RMSD 2.67 Å
- 6T15 chain P against the predicted model P08067: TM-score 0.80, RMSD 2.78 Å
- 6T15 chain E against the predicted model P08067: TM-score 0.80, RMSD 2.80 Å
Elsewhere
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