UniProt P07342
Acetolactate synthase catalytic subunit, mitochondrial (P07342)
Acetolactate synthase catalytic subunit, mitochondrial (UniProt P07342), EC 2.2.1.6: 25 experimental structures on GenesisL1, 14 ligands bound, 51 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P07342
- Protein
- Acetolactate synthase catalytic subunit, mitochondrial
- EC
- 2.2.1.6
- Experimental structures
- 25
- Predicted models
- 0
- Ligands
- 14
- Pockets
- 51 · 3 records with a druggable one
Structures
25 records of P07342 in the MolNFT archive: 25 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1JSC | Crystal Structure of the Catalytic Subunit of Yeast Acetohydroxyacid Synthase: A target for… | x-ray diffraction | A, B | — | — |
| 1JSC | Crystal structure of the catalytic subunit of yeast acetohydroxyacid synthase: a target for… | x-ray diffraction | A, B | — | — |
| 1N0H | Crystal Structure of Yeast Acetohydroxyacid Synthase in Complex with a Sulfonylurea Herbicide… | x-ray diffraction | A, B | — | — |
| 1N0H | Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide… | x-ray diffraction | A, B | — | — |
| 1T9A | Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide… | x-ray diffraction | A, B | — | — |
| 1T9A | Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide… | x-ray diffraction | A, B | — | — |
| 1T9B | Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide… | x-ray diffraction | A, B | — | — |
| 1T9B | Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide… | x-ray diffraction | A, B | — | — |
| 1T9C | Crystal Structure Of Yeast Acetohydroxyacid Synthase In Complex With A Sulfonylurea Herbicide… | x-ray diffraction | A, B | — | — |
| 1T9C | Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide… | x-ray diffraction | A, B | — | — |
| 1T9D | Crystal Structure Of Yeast Acetohydroxyacid Synthase In Complex With A Sulfonylurea Herbicide… | x-ray diffraction | A, B, C, D | — | — |
| 1T9D | Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide… | x-ray diffraction | A, B, C, D | — | — |
| 5FEM | Saccharomyces cerevisiae Acetohydroxyacid Synthase in complex with bensulfuron methyl | x-ray diffraction | A, B | MG, FAD, 60G, TPP | — |
| 5FEM | Saccharomyces cerevisiae acetohydroxyacid synthase in complex with bensulfuron methyl | x-ray diffraction | A, B | — | — |
| 5IMS | Saccharomyces cerevisiae acetohydroxyacid synthase | x-ray diffraction | A, B | K, FAD, MG, TPP, OXY, PO4 | — |
| 5IMS | Saccharomyces cerevisiae acetohydroxyacid synthase | x-ray diffraction | A, B | — | — |
| 5WKC | Saccharomyces cerevisiae acetohydroxyacid synthase in complex with the herbicide penoxsulam | x-ray diffraction | A, B, E, D | MG, PXD, FAD, F50, AUJ, TP9 | 20 (best 0.86) |
| 5WKC | Saccharomyces cerevisiae acetohydroxyacid synthase in complex with the herbicide penoxsulam | x-ray diffraction | A, B, E, D | MG, PXD, FAD, F50, AUJ, TP9 | — |
| 6BD3 | Saccharomyces cerevisiae acetohydroxyacid synthase | x-ray diffraction | A, B | K, MG, TPP, OXY, CO2, FAD | — |
| 6BD3 | Saccharomyces cerevisiae acetohydroxyacid synthase | x-ray diffraction | A, B | K, MG, TPP, OXY, CO2, FAD | — |
| 6BD9 | Saccharomyces cerevisiae acetohydroxyacid synthase | x-ray diffraction | A, B | K, MG, FAD, TPP, PYR, OXY | 11 (best 0.84) |
| 6BD9 | Saccharomyces cerevisiae acetohydroxyacid synthase | x-ray diffraction | A, B | K, MG, FAD, TPP, PYR, OXY | — |
| 6U9D | Saccharomyces cerevisiae acetohydroxyacid synthase | x-ray diffraction | A, B, E, F, I, J, M, N, Q, R, U, V | TPP, MG, FAD, 60G | 20 (best 0.88) |
| 6U9D | Saccharomyces cerevisiae acetohydroxyacid synthase | x-ray diffraction | A, B, E, F, I, J, M, N, Q, R, U, V | TPP, MG, FAD, 60G | — |
| P07342 | AlphaFold monomer V2.0 prediction for acetolactate synthase catalytic subunit, mitochondrial… | — | — | — |
Ligands
- FAD · Flavin-adenine dinucleotide · in 10 records
- MG · Magnesium ion · in 10 records
- TPP · Thiamine diphosphate · in 8 records
- K · Potassium ion · in 5 records
- OXY · Oxygen molecule · in 5 records
- PO4 · Phosphate ion · in 5 records
- 60G · methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate · in 3 records
- AUJ · 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-2-[(1~{S})-1-(dioxidanyl)-1-oxidanyl-ethyl]-4-methyl-1, 3-thiazol-5-yl]ethyl phosphono hydrogen phosphate · in 2 records
- CO2 · Carbon dioxide · in 2 records
- F50 · Ethaneperoxoic acid · in 2 records
- HTL · 2-acetyl-thiamine diphosphate · in 2 records
- PXD · 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy[1,2, 4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl) benzenesulfonamide · in 2 records
- PYR · Pyruvic acid · in 2 records
- TP9 · (3Z)-4-{[(4-amino-2-methylpyrimidin-5-yl)methyl]amino}-3-mercaptopent-3-en-1-yl trihydrogen diphosphate · in 2 records
Elsewhere
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