UniProt P06653
Autolysin (P06653)
Autolysin (UniProt P06653), EC 3.5.1.28: 13 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P06653
- Protein
- Autolysin
- EC
- 3.5.1.28
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 1 · 0 records with a druggable one
Structures
14 records of P06653 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1GVM | Choline binding domain of the major autolysin (C-lyta) from streptococcus pneumoniae | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1GVM | Choline binding domain of the major autolysin (C-lyta) from streptococcus pneumoniae | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1H8G | C-terminal domain of the major autolysin (C-LytA) from Streptococcus pneumoniae | x-ray diffraction | A, B | — | — |
| 1H8G | C-terminal domain of the major autolysin (C-lyta) from streptococcus pneumoniae | x-ray diffraction | A, B | — | — |
| 1HCX | Choline binding domain of the major autolysin (C-LytA) from Streptococcus pneumoniae | x-ray diffraction | A, B | — | — |
| 1HCX | Choline binding domain of the major autolysin (C-lyta) from streptococcus pneumoniae | x-ray diffraction | A, B | — | — |
| 2BML | Ofloxacin-like antibiotics inhibit pneumococcal cell wall degrading virulence factors | x-ray diffraction | A, B | — | — |
| 2BML | Ofloxacin-like antibiotics inhibit pneumococcal cell wall degrading virulence factors | x-ray diffraction | A, B | — | — |
| 4IVV | Catalytic amidase domain of the major autolysin LytA from Streptococcus pneumaniae | x-ray diffraction | A | — | — |
| 4IVV | Catalytic amidase domain of the major autolysin lyta from streptococcus pneumaniae | x-ray diffraction | A | — | — |
| 4X36 | Crystal structure of the autolysin LytA from Streptococcus pneumoniae TIGR4 | x-ray diffraction | A | ZN, CHT | 1 (best 0.41) |
| 4X36 | Crystal structure of the autolysin lyta from streptococcus pneumoniae TIGR4 | x-ray diffraction | A | — | — |
| 5CTV | Catalytic domain of lyta, the major autolysin of streptococcus pneumoniae, (C60A, H133A, C136A… | x-ray diffraction | A | — | — |
| P06653 | AlphaFold monomer V2.0 prediction for autolysin (P06653) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4IVV chain A against the predicted model P06653: TM-score 0.98, RMSD 0.55 Å
- 4IVV chain A against the predicted model P06653: TM-score 0.98, RMSD 0.55 Å
- 5CTV chain A against the predicted model P06653: TM-score 0.98, RMSD 0.58 Å
- 1GVM chain E against the predicted model P06653: TM-score 0.95, RMSD 0.94 Å
- 1GVM chain E against the predicted model P06653: TM-score 0.95, RMSD 0.94 Å
- 1GVM chain A against the predicted model P06653: TM-score 0.95, RMSD 1.05 Å
- 1GVM chain A against the predicted model P06653: TM-score 0.95, RMSD 1.05 Å
- 2BML chain A against the predicted model P06653: TM-score 0.95, RMSD 1.06 Å
- 2BML chain A against the predicted model P06653: TM-score 0.95, RMSD 1.06 Å
- 1GVM chain D against the predicted model P06653: TM-score 0.95, RMSD 1.03 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.