UniProt P05979
P05979
P05979 (UniProt P05979): 41 experimental structures on GenesisL1, 6 ligands bound. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P05979
- Experimental structures
- 41
- Predicted models
- 0
- Ligands
- 6
Structures
41 records of P05979 in the MolNFT archive: 41 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1CQE | Prostaglandin H2 synthase-1 complex with flurbiprofen | x-ray diffraction | A, B | — | — |
| 1CQE | Prostaglandin H2 synthase-1 complex with flurbiprofen | x-ray diffraction | A, B | — | — |
| 1EBV | Ovine pghs-1 complexed with salicyl hydroxamic acid | x-ray diffraction | A | — | — |
| 1EBV | Ovine pghs-1 complexed with salicyl hydroxamic acid | x-ray diffraction | A | — | — |
| 1EQG | The 2.6 ångström model of ovine COX-1 complexed with ibuprofen | x-ray diffraction | A, B | — | — |
| 1EQG | The 2.6 ångström model of ovine COX-1 complexed with ibuprofen | x-ray diffraction | A, B | — | — |
| 1EQH | The 2.7 ångström model of ovine COX-1 complexed with flurbiprofen | x-ray diffraction | A, B | — | — |
| 1EQH | The 2.7 ångström model of ovine COX-1 complexed with flurbiprofen | x-ray diffraction | A, B | — | — |
| 1HT5 | The 2.75 ångström resolution model of ovine COX-1 complexed with methyl ester flurbiprofen | x-ray diffraction | A, B | — | — |
| 1HT5 | The 2.75 ångström resolution model of ovine COX-1 complexed with methyl ester flurbiprofen | x-ray diffraction | A, B | — | — |
| 1HT8 | The 2.7 ångström resolution model of ovine COX-1 complexed with alclofenac | x-ray diffraction | A, B | — | — |
| 1HT8 | The 2.7 ångström resolution model of ovine COX-1 complexed with alclofenac | x-ray diffraction | A, B | — | — |
| 1PRH | The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1 | x-ray diffraction | A, B | — | — |
| 1PRH | The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1 | x-ray diffraction | A, B | — | — |
| 1U67 | Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostagladin H Synthase-1 that Forms… | x-ray diffraction | A | — | — |
| 1U67 | Crystal structure of arachidonic acid bound to a mutant of prostagladin H synthase-1 that forms… | x-ray diffraction | A | — | — |
| 2AYL | 2.0 Angstrom Crystal Structure of Manganese Protoporphyrin IX-reconstituted Ovine Prostaglandin H2… | x-ray diffraction | A, B | — | — |
| 2AYL | 2.0 ångström crystal structure of manganese protoporphyrin IX- reconstituted ovine prostaglandin H2… | x-ray diffraction | A, B | — | — |
| 2OYE | Indomethacin-(R)-alpha-ethyl-ethanolamide bound to Cyclooxygenase-1 | x-ray diffraction | P | — | — |
| 2OYE | Indomethacin-(R)-alpha-ethyl-ethanolamide bound to cyclooxygenase-1 | x-ray diffraction | P | — | — |
| 2OYU | Indomethacin-(S)-alpha-ethyl-ethanolamide bound to Cyclooxygenase-1 | x-ray diffraction | P | — | — |
| 2OYU | Indomethacin-(S)-alpha-ethyl-ethanolamide bound to cyclooxygenase-1 | x-ray diffraction | P | — | — |
| 3KK6 | Crystal Structure of Cyclooxygenase-1 in complex with celecoxib | x-ray diffraction | A, B | — | — |
| 3KK6 | Crystal structure of cyclooxygenase-1 in complex with celecoxib | x-ray diffraction | A, B | — | — |
| 3N8V | Crystal Structure of Unoccupied Cyclooxygenase-1 | x-ray diffraction | A, B | — | — |
| 3N8V | Crystal structure of unoccupied cyclooxygenase-1 | x-ray diffraction | A, B | — | — |
| 3N8W | Crystal Structure of R120Q/Native Cyclooxygenase-1 Heterodimer mutant in complex with Flurbiprofen | x-ray diffraction | A, B | — | — |
| 3N8W | Crystal structure of R120Q/NATIVE cyclooxygenase-1 heterodimer mutant in complex with flurbiprofen | x-ray diffraction | A, B | — | — |
| 3N8X | Crystal Structure of Cyclooxygenase-1 in Complex with Nimesulide | x-ray diffraction | A, B | — | — |
| 3N8X | Crystal structure of cyclooxygenase-1 in complex with nimesulide | x-ray diffraction | A, B | — | — |
| 3N8Y | Structure of Aspirin Acetylated Cyclooxygenase-1 in Complex with Diclofenac | x-ray diffraction | A, B | — | — |
| 3N8Y | Structure of aspirin acetylated cyclooxygenase-1 in complex with diclofenac | x-ray diffraction | A, B | — | — |
| 3N8Z | Crystal Structure of Cyclooxygenase-1 in Complex with Flurbiprofen | x-ray diffraction | A, B | — | — |
| 3N8Z | Crystal structure of cyclooxygenase-1 in complex with flurbiprofen | x-ray diffraction | A, B | — | — |
| 4O1Z | Crystal Structure of Ovine Cyclooxygenase-1 Complex with Meloxicam | x-ray diffraction | A, B | — | — |
| 4O1Z | Crystal structure of ovine cyclooxygenase-1 complex with meloxicam | x-ray diffraction | A, B | — | — |
| 5U6X | COX-1:P6 complex structure | x-ray diffraction | A, B | NAG, MAN, HEM, P6A | — |
| 5U6X | COX-1:P6 complex structure | x-ray diffraction | A, B | NAG, MAN, HEM, P6A | — |
| 5WBE | COX-1:MOFEZOLAC complex structure | x-ray diffraction | A, B | NAG, MAN, HEM, 63X | — |
| 7JXT | Ovine COX-1 in complex with the subtype-selective derivative 2A | x-ray diffraction | A, B | NAG, HEM, W8M | — |
| P05979 | AlphaFold monomer V2.0 prediction for prostaglandin G/H synthase 1 (P05979) | — | — | — |
Ligands
- HEM · Protoporphyrin IX containing Fe · in 4 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
- MAN · alpha-D-mannopyranose · in 3 records
- P6A · 3-(5-chlorofuran-2-yl)-5-methyl-4-phenyl-1,2-oxazole · in 2 records
- 63X · Mofezolac · in 1 record
- W8M · 2-[4,5-bis(2-chlorophenyl)-1H-imidazol-2-yl]-6-(prop-2-en-1-yl)phenyl methoxyacetate · in 1 record
Elsewhere
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