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Ligand · MXM

MXM · 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

MXM, 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide (C14 H13 N3 O4 S2, 351.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its…

Component
MXM
Formula
C14 H13 N3 O4 S2
Class
ligand
Structures
4
PDB entries
2

Binding sites

MXM in 4 structures; the first of them:

  • 4M11 · Crystal Structure of Murine Cyclooxygenase-2 Complex with Meloxicam · MXM A606 · binds MET113, VAL116, LEU117, ARG120, ILE345, VAL349, LEU352, TYR355 and 11 more
  • 4O1Z · Crystal Structure of Ovine Cyclooxygenase-1 Complex with Meloxicam · MXM A807 · binds MET113, VAL116, LEU117, ARG120, ILE345, VAL349, LEU352, TYR355 and 12 more
  • 4M11 · Crystal structure of murine cyclooxygenase-2 complex with meloxicam · MXM A606 · binds MET113, VAL116, LEU117, ARG120, ILE345, VAL349, LEU352, TYR355 and 11 more
  • 4O1Z · Crystal structure of ovine cyclooxygenase-1 complex with meloxicam · MXM A807 · binds MET113, VAL116, LEU117, ARG120, ILE345, VAL349, LEU352, TYR355 and 12 more

Residues it binds most

LEU 12, VAL 12, MET 12, ILE 12, SER 12, TYR 12, ALA 12, ARG 12, GLY 12, PHE 12 (residue and the binding sites it lines).

Found with

  • HEM · Protoporphyrin IX containing Fe
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • BOG · octyl beta-D-glucopyranoside

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