UniProt P05747

60S ribosomal protein L29 (P05747)

60S ribosomal protein L29 (UniProt P05747): 58 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: P05747
Protein: 60S ribosomal protein L29
Experimental structures: 58
Predicted models: 1
Ligands: 3
Pockets: 19 · 10 records with a druggable one

Structures

59 records of P05747 in the MolNFT archive: 58 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
3J6X	S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II)	electron microscopy	69	—	—
3J6Y	S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I)	electron microscopy	69	—	—
3J77	Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class…	electron microscopy	79	—	—
3J78	Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class…	electron microscopy	79	—	—
4U3M	Crystal structure of Anisomycin bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4U3N	Crystal structure of CCA trinucleotide bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4U3U	Crystal structure of Cycloheximide bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4U4N	Crystal structure of Edeine bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4U4O	Crystal structure of Geneticin bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4U4Q	Crystal structure of Homoharringtonine bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4U4R	Crystal structure of Lactimidomycin bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4U4U	Crystal structure of Lycorine bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4U4Y	Crystal structure of Pactamycin bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4U4Z	Crystal structure of Phyllanthoside bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4U50	Crystal structure of Verrucarin bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4U51	Crystal structure of Narciclasine bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4U52	Crystal structure of Nagilactone C bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4U53	Crystal structure of Deoxynivalenol bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4U55	Crystal structure of Cryptopleurine bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4U56	Crystal structure of Blasticidin S bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4U6F	Crystal structure of T-2 toxin bound to the yeast 80S ribosome	x-ray diffraction	N9, n9	—	—
4V6I	Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces…	electron microscopy	Bd	—	—
4V88	The structure of the eukaryotic ribosome at 3.0 A resolution.	x-ray diffraction	Bb, Db	—	—
4V8T	Cryo-EM Structure of the 60S Ribosomal Subunit in Complex with Arx1 and Rei1	electron microscopy	b	—	—
4V8Y	Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex	electron microscopy	Bb	—	—
4V8Z	Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex	electron microscopy	Bb	—	—
5GAK	Yeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5A	electron microscopy	d	—	3 (best 0.88)
5H4P	Structural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1	electron microscopy	b	—	—
5JUP	Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura…	electron microscopy	GA	—	—
5JUS	Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura…	electron microscopy	GA	—	—
5JUU	Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura…	electron microscopy	GA	—	3 (best 0.88)
5MC6	Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae	electron microscopy	AV	—	—
5MEI	Crystal structure of Agelastatin A bound to the 80S ribosome	x-ray diffraction	AC, DD	MG, OHX	—
6GQ1	Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP/sordarin)	electron microscopy	b	—	—
6GQB	Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GDP+AlF4/sordarin)	electron microscopy	b	—	—
6GQV	Cryo-EM recosntruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP)	electron microscopy	b	—	—
6HD7	Cryo-EM structure of the ribosome-NatA complex	electron microscopy	d	—	—
6HHQ	Crystal structure of compound C45 bound to the yeast 80S ribosome	x-ray diffraction	AC, DD	MG, OHX	—
6I7O	The structure of a di-ribosome (disome) as a unit for RQC and NGD quality control pathways…	electron microscopy	AV, XV	—	—
6N8J	Cryo-EM structure of late nuclear (LN) pre-60S ribosomal subunit	electron microscopy	o	—	1 (best 0.88)
6N8K	Cryo-EM structure of early cytoplasmic-immediate (ECI) pre-60S ribosomal subunit	electron microscopy	o	—	—
6N8L	Cryo-EM structure of early cytoplasmic-late (ECL) pre-60S ribosomal subunit	electron microscopy	o	—	—
6N8M	Cryo-EM structure of pre-Lsg1 (PL) pre-60S ribosomal subunit	electron microscopy	o	—	—
6N8N	Cryo-EM structure of Lsg1-engaged (LE) pre-60S ribosomal subunit	electron microscopy	o	—	—
6N8O	Cryo-EM structure of Rpl10-inserted (RI) pre-60S ribosomal subunit	electron microscopy	o	—	—
6QIK	Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles	electron microscopy	a	—	—
6S05	Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles	electron microscopy	a	—	2 (best 0.86)
6T83	Structure of yeast disome (di-ribosome) stalled on poly(A) tract.	electron microscopy	by, M	—	—
6TNU	Yeast 80S ribosome in complex with eIF5A and decoding A-site and P-site tRNAs.	electron microscopy	AV	—	—
6Z6J	Cryo-EM structure of yeast Lso2 bound to 80S ribosomes under native condition	electron microscopy	Lb	—	1 (best 0.87)
7MPI	Stm1 bound vacant 80S structure isolated from cbf5-D95A	electron microscopy	Ab	MG	—
7MPJ	Stm1 bound vacant 80S structure isolated from wild-type	electron microscopy	Ab	MG	2 (best 0.88)
7NRC	Structure of the yeast Gcn1 bound to a leading stalled 80S ribosome with Rbg2, Gir2, A- and P-tRNA…	electron microscopy	Ld	—	3 (best 0.89)
7ZS5	Structure of 60S ribosomal subunit from S. cerevisiae with eIF6 and tRNA	electron microscopy	Bc	—	—
7ZW0	FAP-80S Complex - Rotated state	electron microscopy	Le	MG	2 (best 0.88)
8CG8	Translocation intermediate 3 (TI-3) of 80S S. cerevisiae ribosome with ligands and eEF2 in the…	electron microscopy	N	—	1 (best 0.86)
8CIV	Translocation intermediate 5 (TI-5) of 80S S. cerevisiae ribosome with ligands and eEF2 in the…	electron microscopy	N	MG	1 (best 0.87)
8P8N	Mouse RPL39 integrated into the yeast 60S ribosomal subunit	electron microscopy	RB	CL	—
P05747	AlphaFold monomer V2.0 prediction for 60S ribosomal protein L29 (P05747)	predicted	A	—	—

Ligands

MG · Magnesium ion · in 6 records
OHX · osmium (III) hexammine · in 2 records
CL · Chloride ion · in 1 record

Experiment against prediction

8CIV chain N against the predicted model P05747: TM-score 0.93, RMSD 0.75 Å
8CG8 chain N against the predicted model P05747: TM-score 0.92, RMSD 0.84 Å
7NRC chain Ld against the predicted model P05747: TM-score 0.91, RMSD 0.91 Å
6Z6J chain Lb against the predicted model P05747: TM-score 0.91, RMSD 0.88 Å
5JUP chain GA against the predicted model P05747: TM-score 0.91, RMSD 0.97 Å
6TNU chain AV against the predicted model P05747: TM-score 0.91, RMSD 0.93 Å
7ZS5 chain Bc against the predicted model P05747: TM-score 0.91, RMSD 0.89 Å
7MPJ chain Ab against the predicted model P05747: TM-score 0.90, RMSD 0.98 Å
4V8Y chain Bb against the predicted model P05747: TM-score 0.90, RMSD 0.90 Å
4V8Z chain Bb against the predicted model P05747: TM-score 0.90, RMSD 0.90 Å

Elsewhere

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