UniProt P05020
CAD protein,Dihydroorotase,CAD protein (P05020)
CAD protein,Dihydroorotase,CAD protein (UniProt P05020), EC 2.1.3.2, 3.5.2.3: 31 experimental structures on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P05020
- Protein
- CAD protein,Dihydroorotase,CAD protein
- EC
- 2.1.3.2, 3.5.2.3, 6.3.5.5
- Experimental structures
- 31
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
31 records of P05020 in the MolNFT archive: 31 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1J79 | Molecular Structure of Dihydroorotase: A Paradigm for Catalysis Through the Use of a Binuclear… | x-ray diffraction | A, B | — | — |
| 1J79 | Molecular structure of dihydroorotase: a paradigm for catalysis through the use of a binuclear… | x-ray diffraction | A, B | — | — |
| 1XGE | Dihydroorotase from Escherichia coli: Loop Movement and Cooperativity between subunits | x-ray diffraction | A, B | — | — |
| 1XGE | Dihydroorotase from escherichia COLI: loop movement and cooperativity between subunits | x-ray diffraction | A, B | — | — |
| 2E25 | The Crystal Structure of the T109S mutant of E. coli Dihydroorotase complexed with an inhibitor… | x-ray diffraction | A | — | — |
| 2E25 | The crystal structure of the T109S mutant of E. COLI dihydroorotase complexed with an inhibitor… | x-ray diffraction | A | — | — |
| 2EG6 | The crystal structure of the ligand-free dihydroorotase from E. coli | x-ray diffraction | A, B | — | — |
| 2EG6 | The crystal structure of the ligand-free dihydroorotase from E. COLI | x-ray diffraction | A, B | — | — |
| 2EG7 | The crystal structure of E. coli dihydroorotase complexed with HDDP | x-ray diffraction | A, B | — | — |
| 2EG7 | The crystal structure of E. COLI dihydroorotase complexed with hddp | x-ray diffraction | A, B | — | — |
| 2EG8 | The crystal structure of E. coli dihydroorotase complexed with 5-fluoroorotic acid | x-ray diffraction | A, B | — | — |
| 2EG8 | The crystal structure of E. COLI dihydroorotase complexed with 5- fluoroorotic acid | x-ray diffraction | A, B | — | — |
| 2Z24 | Thr110Ser dihydroorotase from E. coli | x-ray diffraction | A, B | — | — |
| 2Z24 | THR110SER dihydroorotase from E. COLI | x-ray diffraction | A, B | — | — |
| 2Z25 | Thr110Val dihydroorotase from E. coli | x-ray diffraction | A, B | — | — |
| 2Z25 | THR110VAL dihydroorotase from E. COLI | x-ray diffraction | A, B | — | — |
| 2Z26 | Thr110Ala dihydroorotase from E. coli | x-ray diffraction | A, B | — | — |
| 2Z26 | THR110ALA dihydroorotase from E. COLI | x-ray diffraction | A, B | — | — |
| 2Z27 | Thr109Ser dihydroorotase from E. coli | x-ray diffraction | A, B | — | — |
| 2Z27 | THR109SER dihydroorotase from E. COLI | x-ray diffraction | A, B | — | — |
| 2Z28 | Thr109Val dihydroorotase from E. coli | x-ray diffraction | A, B | — | — |
| 2Z28 | THR109VAL dihydroorotase from E. COLI | x-ray diffraction | A, B | — | — |
| 2Z29 | Thr109Ala dihydroorotase from E. coli | x-ray diffraction | A, B | — | — |
| 2Z29 | THR109ALA dihydroorotase from E. COLI | x-ray diffraction | A, B | — | — |
| 2Z2A | Thr109Gly dihydroorotase from E. coli | x-ray diffraction | A, B | — | — |
| 2Z2A | THR109GLY dihydroorotase from E. COLI | x-ray diffraction | A, B | — | — |
| 2Z2B | Deletion 107-116 mutant of dihydroorotase from E. coli | x-ray diffraction | A | — | — |
| 2Z2B | Deletion 107-116 mutant of dihydroorotase from E. COLI | x-ray diffraction | A | — | — |
| 6HG1 | Hybrid dihydroorotase domain of human CAD with E. coli flexible loop in apo state | x-ray diffraction | A | ZN | 3 (best 0.57) |
| 6HG1 | Hybrid dihydroorotase domain of human cad with E. COLI flexible loop in apo state | x-ray diffraction | A | ZN | — |
| P05020 | AlphaFold monomer V2.0 prediction for dihydroorotase (P05020) | — | — | — |
Ligands
- ZN · Zinc ion · in 2 records
Elsewhere
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