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UniProt P04456

60S ribosomal protein L25 (P04456)

60S ribosomal protein L25 (UniProt P04456): 188 experimental structures on GenesisL1, 3 ligands bound, 127 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P04456
Protein
60S ribosomal protein L25
Experimental structures
188
Predicted models
0
Ligands
3
Pockets
127 · 78 records with a druggable one

Structures

188 records of P04456 in the MolNFT archive: 188 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
2WW9Cryo-EM structure of the active yeast Ssh1 complex bound to the yeast 80S ribosomeelectron microscopyK——
2WW9Cryo-EM structure of the active yeast SSH1 complex bound to the yeast 80S ribosomeelectron microscopyK——
2WWACryo-EM structure of idle yeast Ssh1 complex bound to the yeast 80S ribosomeelectron microscopyK——
2WWACryo-EM structure of idle yeast SSH1 complex bound to the yeast 80S ribosomeelectron microscopyK——
3J6XS. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II)electron microscopy65——
3J6YS. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I)electron microscopy65——
3J77Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class…electron microscopy75——
3J78Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class…electron microscopy75——
3JCTCryo-em structure of eukaryotic pre-60S ribosomal subunitselectron microscopyX——
4U3MCrystal structure of Anisomycin bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4U3NCrystal structure of CCA trinucleotide bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4U3UCrystal structure of Cycloheximide bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4U4NCrystal structure of Edeine bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4U4OCrystal structure of Geneticin bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4U4QCrystal structure of Homoharringtonine bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4U4RCrystal structure of Lactimidomycin bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4U4UCrystal structure of Lycorine bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4U4YCrystal structure of Pactamycin bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4U4ZCrystal structure of Phyllanthoside bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4U50Crystal structure of Verrucarin bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4U51Crystal structure of Narciclasine bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4U52Crystal structure of Nagilactone C bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4U53Crystal structure of Deoxynivalenol bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4U55Crystal structure of Cryptopleurine bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4U56Crystal structure of Blasticidin S bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4U6FCrystal structure of T-2 toxin bound to the yeast 80S ribosomex-ray diffractionN5, n5——
4V4BStructure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models…electron microscopyBT——
4V6ILocalization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces…electron microscopyBX——
4V7FArx1 pre-60S particle.electron microscopyW——
4V7FARX1 pre-60S particle.electron microscopyW——
4V7RYeast 80S ribosome.x-ray diffractionBW, DW——
4V88The structure of the eukaryotic ribosome at 3.0 A resolution.x-ray diffractionBX, DX——
4V8TCryo-EM Structure of the 60S Ribosomal Subunit in Complex with Arx1 and Rei1electron microscopyX——
4V8YCryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complexelectron microscopyBX——
4V8ZCryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complexelectron microscopyBX——
5DGFComplex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA…x-ray diffractionN5, n5—1 (best 0.87)
5DGVComplex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA…x-ray diffractionN5, n5—1 (best 0.87)
5FCIStructure of the vacant uL3 W255C mutant 80S yeast ribosomex-ray diffractionN5, n5MG, OHX—
5GAKYeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5Aelectron microscopyZ——
5H4PStructural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1electron microscopyX——
5I4LCrystal structure of Amicoumacin A bound to the yeast 80S ribosomex-ray diffractionN5, n5MG, OHX1 (best 0.87)
5JCSCryo-EM structure of the RIX1-REA1 pre-60S particleelectron microscopyX——
5JUOSaccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura…electron microscopyCA—2 (best 0.88)
5JUPSaccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura…electron microscopyCA——
5JUSSaccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura…electron microscopyCA——
5JUTSaccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura…electron microscopyCA——
5JUUSaccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura…electron microscopyCA—1 (best 0.87)
5LYBCrystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA…x-ray diffractionN5, n5MG, OHX1 (best 0.87)
5M1JNonstop ribosomal complex bound with Dom34 and Hbs1electron microscopyX5MG1 (best 0.85)
5MC6Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiaeelectron microscopyAH——
5MEICrystal structure of Agelastatin A bound to the 80S ribosomex-ray diffraction8, CZMG, OHX—
5NDGCrystal structure of geneticin (G418) bound to the yeast 80S ribosomex-ray diffractionN5, n5MG1 (best 0.89)
5NDVCrystal structure of Paromomycin bound to the yeast 80S ribosomex-ray diffractionN5, n5MG—
5NDWCrystal structure of aminoglycoside TC007 bound to the yeast 80S ribosomex-ray diffractionn5, N5MG—
5OBMCrystal structure of Gentamicin bound to the yeast 80S ribosomex-ray diffractionN5, n5MG, LLL2 (best 0.88)
5T62Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome…electron microscopyk—1 (best 0.86)
5T6RNmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome…electron microscopyk——
5TGACrystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA…x-ray diffractionN5, n5MG, OHX2 (best 0.87)
5TGMCrystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA…x-ray diffractionN5, n5MG, OHX—
6ELZState E (TAP-Flag-Ytm1 E80A) - Visualizing the assembly pathway of nucleolar pre-60S ribosomeselectron microscopyX—1 (best 0.86)

128 records more on the page itself.

Ligands

  • MG · Magnesium ion · in 52 records
  • OHX · osmium (III) hexammine · in 8 records
  • LLL · (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-diamino-3-((2R, 3R,6S)-3-amino-6-(aminomethyl)-tetrahydro-2H-pyran-2-yloxy)-2-hydroxycyclohexyloxy)-5-methyl-4-(methylamino)-tetrahydro-2H-pyran-3,5-diol · in 1 record

Elsewhere

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