UniProt P04449
60S ribosomal protein L24-A (P04449)
60S ribosomal protein L24-A (UniProt P04449): 124 experimental structures on GenesisL1, 4 ligands bound, 6 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P04449
- Protein
- 60S ribosomal protein L24-A
- Experimental structures
- 124
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 6 · 6 records with a druggable one
Structures
124 records of P04449 in the MolNFT archive: 124 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2X7N | Mechanism of eIF6s anti-association activity | electron microscopy | D | — | — |
| 2X7N | Mechanism of EIF6S anti-association activity | electron microscopy | D | — | — |
| 3J6X | S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II) | electron microscopy | 64 | — | — |
| 3J6Y | S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I) | electron microscopy | 64 | — | — |
| 3J77 | Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class… | electron microscopy | 74 | — | — |
| 3J78 | Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class… | electron microscopy | 74 | — | — |
| 4U3M | Crystal structure of Anisomycin bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4U3N | Crystal structure of CCA trinucleotide bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4U3U | Crystal structure of Cycloheximide bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4U4N | Crystal structure of Edeine bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4U4O | Crystal structure of Geneticin bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4U4Q | Crystal structure of Homoharringtonine bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4U4R | Crystal structure of Lactimidomycin bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4U4U | Crystal structure of Lycorine bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4U4Y | Crystal structure of Pactamycin bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4U4Z | Crystal structure of Phyllanthoside bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4U50 | Crystal structure of Verrucarin bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4U51 | Crystal structure of Narciclasine bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4U52 | Crystal structure of Nagilactone C bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4U53 | Crystal structure of Deoxynivalenol bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4U55 | Crystal structure of Cryptopleurine bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4U56 | Crystal structure of Blasticidin S bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4U6F | Crystal structure of T-2 toxin bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | — | — |
| 4V4B | Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models… | electron microscopy | BS | — | — |
| 4V6I | Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces… | electron microscopy | BZ | — | — |
| 4V7R | Yeast 80S ribosome. | x-ray diffraction | BV, DV | — | — |
| 4V88 | The structure of the eukaryotic ribosome at 3.0 A resolution. | x-ray diffraction | BW, DW | — | — |
| 4V8T | Cryo-EM Structure of the 60S Ribosomal Subunit in Complex with Arx1 and Rei1 | electron microscopy | W | — | — |
| 4V8Y | Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex | electron microscopy | BW | — | — |
| 4V8Z | Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex | electron microscopy | BW | — | — |
| 5DGF | Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA… | x-ray diffraction | N4, n4 | — | — |
| 5DGV | Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA… | x-ray diffraction | N4, n4 | — | — |
| 5FCI | Structure of the vacant uL3 W255C mutant 80S yeast ribosome | x-ray diffraction | N4, n4 | MG | — |
| 5GAK | Yeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5A | electron microscopy | Y | — | — |
| 5H4P | Structural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1 | electron microscopy | W | — | — |
| 5I4L | Crystal structure of Amicoumacin A bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | MG | — |
| 5JUO | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | BA | — | — |
| 5JUP | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | BA | — | — |
| 5JUS | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | BA | — | — |
| 5JUT | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | BA | — | — |
| 5JUU | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | BA | — | — |
| 5LYB | Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA… | x-ray diffraction | N4, n4 | MG, OHX | — |
| 5M1J | Nonstop ribosomal complex bound with Dom34 and Hbs1 | electron microscopy | W5 | MG | — |
| 5MC6 | Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae | electron microscopy | AE | — | — |
| 5MEI | Crystal structure of Agelastatin A bound to the 80S ribosome | x-ray diffraction | 7, CY | OHX, MG | — |
| 5NDG | Crystal structure of geneticin (G418) bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | MG, GET | — |
| 5NDV | Crystal structure of Paromomycin bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | MG | — |
| 5NDW | Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosome | x-ray diffraction | n4, N4 | MG | — |
| 5OBM | Crystal structure of Gentamicin bound to the yeast 80S ribosome | x-ray diffraction | N4, n4 | MG, LLL | — |
| 5T62 | Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome… | electron microscopy | j | — | — |
| 5T6R | Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome… | electron microscopy | j | — | — |
| 5TGA | Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA… | x-ray diffraction | N4, n4 | OHX, MG | — |
| 5TGM | Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA… | x-ray diffraction | N4, n4 | MG | — |
| 6GQ1 | Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP/sordarin) | electron microscopy | W | — | — |
| 6GQB | Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GDP+AlF4/sordarin) | electron microscopy | W | — | — |
| 6GQV | Cryo-EM recosntruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP) | electron microscopy | W | — | — |
| 6HD7 | Cryo-EM structure of the ribosome-NatA complex | electron microscopy | Y | — | — |
| 6HHQ | Crystal structure of compound C45 bound to the yeast 80S ribosome | x-ray diffraction | 7, CY | MG | — |
| 6I7O | The structure of a di-ribosome (disome) as a unit for RQC and NGD quality control pathways… | electron microscopy | AE, XE | — | — |
| 6N8M | Cryo-EM structure of pre-Lsg1 (PL) pre-60S ribosomal subunit | electron microscopy | j | — | — |
64 records more on the page itself.
Ligands
- MG · Magnesium ion · in 16 records
- OHX · osmium (III) hexammine · in 4 records
- GET · Geneticin · in 1 record
- LLL · (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-diamino-3-((2R, 3R,6S)-3-amino-6-(aminomethyl)-tetrahydro-2H-pyran-2-yloxy)-2-hydroxycyclohexyloxy)-5-methyl-4-(methylamino)-tetrahydro-2H-pyran-3,5-diol · in 1 record
Elsewhere
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