UniProt P04278
Sex hormone-binding globulin (P04278)
Sex hormone-binding globulin (UniProt P04278): 26 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P04278
- Protein
- Sex hormone-binding globulin
- Experimental structures
- 26
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 10 · 5 records with a druggable one
Structures
27 records of P04278 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1D2S | Crystal structure of the N-terminal laminin G-like domain of shbg in complex with… | x-ray diffraction | A | — | — |
| 1D2S | Crystal structure of the N-terminal laminin G-like domain of shbg in complex with… | x-ray diffraction | A | — | — |
| 1F5F | Crystal structure of the N-terminal G-domain of shbg in complex with zinc | x-ray diffraction | A | — | — |
| 1F5F | Crystal structure of the N-terminal G-domain of shbg in complex with zinc | x-ray diffraction | A | — | — |
| 1KDK | The structure of the N-terminal lg domain of shbg in crystals soaked with edta | x-ray diffraction | A | — | — |
| 1KDK | The structure of the N-terminal lg domain of shbg in crystals soaked with edta | x-ray diffraction | A | — | — |
| 1KDM | The crystal structure of the human sex hormone-binding globulin (tetragonal crystal form) | x-ray diffraction | A | — | — |
| 1KDM | The crystal structure of the human sex hormone-binding globulin (tetragonal crystal form) | x-ray diffraction | A | — | — |
| 1LHN | Crystal structure of the N-terminal lg-domain of shbg in complex with… | x-ray diffraction | A | — | — |
| 1LHN | Crystal structure of the N-terminal lg-domain of shbg in complex with… | x-ray diffraction | A | — | — |
| 1LHO | Crystal structure of the N-terminal lg-domain of shbg in complex with… | x-ray diffraction | A | — | — |
| 1LHO | Crystal structure of the N-terminal lg-domain of shbg in complex with… | x-ray diffraction | A | — | — |
| 1LHU | Crystal structure of the N-terminal lg-domain of shbg in complex with estradiol | x-ray diffraction | A | — | — |
| 1LHU | Crystal structure of the N-terminal lg-domain of shbg in complex with estradiol | x-ray diffraction | A | — | — |
| 1LHV | Crystal structure of the N-terminal lg-domain of shbg in complex with norgestrel | x-ray diffraction | A | — | — |
| 1LHV | Crystal structure of the N-terminal lg-domain of shbg in complex with norgestrel | x-ray diffraction | A | — | — |
| 1LHW | Crystal structure of the N-terminal lg-domain of shbg in complex with 2-methoxyestradiol | x-ray diffraction | A | — | — |
| 1LHW | Crystal structure of the N-terminal lg-domain of shbg in complex with 2-methoxyestradiol | x-ray diffraction | A | — | — |
| 6PYA | Sex Hormone-binding globulin mutant E176K in complex with IPI | x-ray diffraction | A | P57, CA | 2 (best 0.80) |
| 6PYA | Sex hormone-binding globulin mutant E176K in complex with ipi | x-ray diffraction | A | P57, CA | — |
| 6PYB | Sex Hormone-binding globulin mutant E176K in complex with DVT | x-ray diffraction | A | P5G, CA | 1 (best 0.72) |
| 6PYB | Sex hormone-binding globulin mutant E176K in complex with dvt | x-ray diffraction | A | P5G, CA | — |
| 6PYF | Sex Hormone-binding globulin mutant E176K in complex with Estradiol | x-ray diffraction | A | CA, EST | 2 (best 0.83) |
| 6PYF | Sex hormone-binding globulin mutant E176K in complex with estradiol | x-ray diffraction | A | CA, EST | — |
| 6ULB | Sex Hormone-binding globulin mutant E176K in complex with Danazol | x-ray diffraction | A | CA, QA1 | 2 (best 0.80) |
| 6ULB | Sex hormone-binding globulin mutant E176K in complex with danazol | x-ray diffraction | A | CA, QA1 | — |
| P04278 | AlphaFold monomer V2.0 prediction for sex hormone-binding globulin (P04278) | predicted | A | — | 3 (best 0.81) |
Ligands
Experiment against prediction
- 6ULB chain A against the predicted model P04278: TM-score 0.98, RMSD 0.75 Å
- 6ULB chain A against the predicted model P04278: TM-score 0.98, RMSD 0.75 Å
- 6PYF chain A against the predicted model P04278: TM-score 0.97, RMSD 0.84 Å
- 6PYF chain A against the predicted model P04278: TM-score 0.97, RMSD 0.84 Å
- 1LHU chain A against the predicted model P04278: TM-score 0.97, RMSD 1.11 Å
- 1LHU chain A against the predicted model P04278: TM-score 0.97, RMSD 1.11 Å
- 1KDM chain A against the predicted model P04278: TM-score 0.97, RMSD 0.96 Å
- 1KDM chain A against the predicted model P04278: TM-score 0.97, RMSD 0.96 Å
- 1F5F chain A against the predicted model P04278: TM-score 0.97, RMSD 1.17 Å
- 1F5F chain A against the predicted model P04278: TM-score 0.97, RMSD 1.17 Å
Elsewhere
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