UniProt P04228
H-2 class II histocompatibility antigen, A-D alpha chain (P04228)
H-2 class II histocompatibility antigen, A-D alpha chain (UniProt P04228): 24 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 18 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P04228
- Protein
- H-2 class II histocompatibility antigen, A-D alpha chain
- Experimental structures
- 24
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 18 · 2 records with a druggable one
Structures
25 records of P04228 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ES0 | Crystal structure of the murine class II allele I-A(G7) complexed with the glutamic acid… | x-ray diffraction | A | — | — |
| 1ES0 | Crystal structure of the murine class II allele I-A(G7) complexed with the glutamic acid… | x-ray diffraction | A | — | — |
| 1F3J | Histocompatibility antigen I-AG7 | x-ray diffraction | A, D | — | — |
| 1F3J | Histocompatibility antigen I-AG7 | x-ray diffraction | A, D | — | — |
| 1IAO | Class II MHC I-ad in complex with ovalbumin peptide 323-339 | x-ray diffraction | A, B | — | — |
| 1IAO | Class II MHC I-ad in complex with ovalbumin peptide 323-339 | x-ray diffraction | A, B | — | — |
| 2IAD | Class II MHC I-ad in complex with an influenza hemagglutinin peptide 126-138 | x-ray diffraction | A | — | — |
| 2IAD | Class II MHC I-ad in complex with an influenza hemagglutinin peptide 126-138 | x-ray diffraction | A | — | — |
| 3CUP | Crystal structure of the MHC class II molecule I-Ag7 in complex with the peptide GAD221-235 | x-ray diffraction | A | — | — |
| 3CUP | Crystal structure of the MHC class II molecule I-AG7 in complex with the peptide GAD221-235 | x-ray diffraction | A | — | — |
| 3MBE | TCR 21.30 in complex with MHC class II I-Ag7HEL(11-27) | x-ray diffraction | A, E | — | — |
| 3MBE | TCR 21.30 in complex with MHC class II I-AG7HEL(11-27) | x-ray diffraction | A, E | — | — |
| 5DMK | Crystal Structure of IAg7 in complex with RLGL-WE14 | x-ray diffraction | A, C, E, G | — | — |
| 5DMK | Crystal structure of IAG7 in complex with rlgl-WE14 | x-ray diffraction | A, C, E, G | — | — |
| 6BLQ | Crystal structure of IAG7 in complex with insulin mimotope P8E9E | x-ray diffraction | A | NAG | — |
| 6BLR | Crystal Structure of IAg7 in complex with insulin mimotope p8E9E6SS | x-ray diffraction | A | — | — |
| 6BLR | Crystal structure of IAG7 in complex with insulin mimotope P8E9E6SS | x-ray diffraction | A | — | — |
| 6BLX | Crystal structure of IAG7 in complex with insulin mimotope P8G9E | x-ray diffraction | A | NAG | — |
| 6DFS | mouse TCR I.29 in complex with IAg7-p8E9E6ss | x-ray diffraction | C | NAG | 6 (best 0.59) |
| 6DFS | Mouse TCR I.29 in complex with IAG7-P8E9E6SS | x-ray diffraction | C | NAG | — |
| 6DFW | TCR 8F10 in complex with IAG7-P8G9E | x-ray diffraction | A, C | — | — |
| 7QHP | Structure of I-AG7 with a bound hybrid insulin peptide | x-ray diffraction | A | — | — |
| 7RDV | Tfh TCR bound to MHC class II iad presenting aggrecan epitope | x-ray diffraction | A | NAG | — |
| 7Z50 | Structure of the highly diabetogenic 4.1-T cell receptor targeting a hybrid insulin peptide bound… | x-ray diffraction | A, C | NAG | 12 (best 0.76) |
| P04228 | AlphaFold monomer V2.0 prediction for H-2 class II histocompatibility antigen, a-D alpha chain… | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 6 records
Experiment against prediction
- 7QHP chain A against the predicted model P04228: TM-score 0.96, RMSD 1.29 Å
- 3CUP chain A against the predicted model P04228: TM-score 0.96, RMSD 1.33 Å
- 3CUP chain A against the predicted model P04228: TM-score 0.96, RMSD 1.33 Å
- 1IAO chain A against the predicted model P04228: TM-score 0.96, RMSD 1.16 Å
- 1IAO chain A against the predicted model P04228: TM-score 0.96, RMSD 1.16 Å
- 7Z50 chain C against the predicted model P04228: TM-score 0.96, RMSD 1.10 Å
- 1F3J chain A against the predicted model P04228: TM-score 0.95, RMSD 1.10 Å
- 1F3J chain A against the predicted model P04228: TM-score 0.95, RMSD 1.10 Å
- 7RDV chain A against the predicted model P04228: TM-score 0.95, RMSD 1.21 Å
- 5DMK chain A against the predicted model P04228: TM-score 0.95, RMSD 1.10 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.