UniProt P04117
Fatty acid-binding protein, adipocyte (P04117)
Fatty acid-binding protein, adipocyte (UniProt P04117): 41 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P04117
- Protein
- Fatty acid-binding protein, adipocyte
- Experimental structures
- 41
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
42 records of P04117 in the MolNFT archive: 41 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1A18 | Phenanthroline modified murine adipocyte lipid binding protein | x-ray diffraction | A | — | — |
| 1A18 | Phenanthroline modified murine adipocyte lipid binding protein | x-ray diffraction | A | — | — |
| 1A2D | Pyridoxamine modified murine adipocyte lipid binding protein | x-ray diffraction | A, B | — | — |
| 1A2D | Pyridoxamine modified murine adipocyte lipid binding protein | x-ray diffraction | A, B | — | — |
| 1AB0 | C1G/V32D/F57H mutant of murine adipocyte lipid binding protein at pH 4.5 | x-ray diffraction | A | — | — |
| 1AB0 | C1G/V32D/F57H mutant of murine adipocyte lipid binding protein at pH 4.5 | x-ray diffraction | A | — | — |
| 1ACD | V32D/F57H mutant of murine adipocyte lipid binding protein | x-ray diffraction | A | — | — |
| 1ACD | V32D/F57H mutant of murine adipocyte lipid binding protein | x-ray diffraction | A | — | — |
| 1ADL | Adipocyte lipid binding protein complexed with arachidonic acid: X-ray crystallographic and… | x-ray diffraction | A | — | — |
| 1ADL | Adipocyte lipid binding protein complexed with arachidonic acid: X-ray crystallographic and… | x-ray diffraction | A | — | — |
| 1ALB | Crystal structure of recombinant murine adipocyte lipid-binding protein | x-ray diffraction | A | — | — |
| 1ALB | Crystal structure of recombinant murine adipocyte lipid-binding protein | x-ray diffraction | A | — | — |
| 1G74 | Toward changing specificity: adipocyte lipid binding protein mutant, oleic acid bound form | x-ray diffraction | A | — | — |
| 1G74 | Toward changing specificity: adipocyte lipid binding protein mutant, oleic acid bound form | x-ray diffraction | A | — | — |
| 1G7N | Toward changing specificity: adipocyte lipid binding protein mutant, apo form | x-ray diffraction | A | — | — |
| 1G7N | Toward changing specificity: adipocyte lipid binding protein mutant, apo form | x-ray diffraction | A | — | — |
| 1LIB | The adipocyte lipid-binding protein at 1.6 ångströms resolution: crystal structures of the… | x-ray diffraction | A | — | — |
| 1LIB | The adipocyte lipid-binding protein at 1.6 ångströms resolution: crystal structures of the… | x-ray diffraction | A | — | — |
| 1LIC | X-ray crystallographic structures of adipocyte lipid binding protein complexed with palmitate and… | x-ray diffraction | A | — | — |
| 1LIC | X-ray crystallographic structures of adipocyte lipid binding protein complexed with palmitate and… | x-ray diffraction | A | — | — |
| 1LID | The adipocyte lipid-binding protein at 1.6 ångströms resolution: crystal structures of the… | x-ray diffraction | A | — | — |
| 1LID | The adipocyte lipid-binding protein at 1.6 ångströms resolution: crystal structures of the… | x-ray diffraction | A | — | — |
| 1LIE | X-ray crystallographic structures of adipocyte lipid binding protein complexed with palmitate and… | x-ray diffraction | A | — | — |
| 1LIE | X-ray crystallographic structures of adipocyte lipid binding protein complexed with palmitate and… | x-ray diffraction | A | — | — |
| 1LIF | The adipocyte lipid-binding protein at 1.6 ångströms resolution: crystal structures of the… | x-ray diffraction | A | — | — |
| 1LIF | The adipocyte lipid-binding protein at 1.6 ångströms resolution: crystal structures of the… | x-ray diffraction | A | — | — |
| 2ANS | Adipocyte lipid binding protein complexed with 1-anilino-8-naphthalene sulfonate | x-ray diffraction | A, B | — | — |
| 2ANS | Adipocyte lipid binding protein complexed with 1-anilino-8-naphthalene sulfonate | x-ray diffraction | A, B | — | — |
| 2Q9S | Linoleic Acid Bound to Fatty Acid Binding Protein 4 | x-ray diffraction | A | — | — |
| 2Q9S | Linoleic acid bound to fatty acid binding protein 4 | x-ray diffraction | A | — | — |
| 2QM9 | Troglitazone Bound to Fatty Acid Binding Protein 4 | x-ray diffraction | A, B | — | — |
| 2QM9 | Troglitazone bound to fatty acid binding protein 4 | x-ray diffraction | A, B | — | — |
| 3HK1 | Identification and Characterization of a Small Molecule Inhibitor of Fatty Acid Binding Proteins | x-ray diffraction | A | — | — |
| 3HK1 | Identification and characterization of a small molecule inhibitor of fatty acid binding proteins | x-ray diffraction | A | — | — |
| 3JS1 | Crystal structure of adipocyte fatty acid binding protein covalently modified with 4-hydroxy-2- nal | x-ray diffraction | A, B | — | — |
| 3JS1 | Crystal structure of adipocyte fatty acid binding protein covalently modified with… | x-ray diffraction | A, B | — | — |
| 3JSQ | Crystal structure of adipocyte fatty acid binding protein non-covalently modified with 4-hydroxy-2… | x-ray diffraction | A | — | — |
| 3JSQ | Crystal structure of adipocyte fatty acid binding protein non- covalently modified with… | x-ray diffraction | A | — | — |
| 5C0N | Development of a monoclonal antibody targeting secreted AP2 to treat diabetes and fatty liver… | x-ray diffraction | A, B | — | — |
| 5D8J | Development of a therapeutic monoclonal antibody targeting secreted aP2 to treat type 2 diabetes. | x-ray diffraction | A | SO4 | 1 (best 0.82) |
| 5D8J | Development of a therapeutic monoclonal antibody targeting secreted AP2 to treat type 2 diabetes. | x-ray diffraction | A | — | — |
| P04117 | AlphaFold monomer V2.0 prediction for fatty acid-binding protein, adipocyte (P04117) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 3HK1 chain A against the predicted model P04117: TM-score 0.99, RMSD 0.37 Å
- 3HK1 chain A against the predicted model P04117: TM-score 0.99, RMSD 0.37 Å
- 1ADL chain A against the predicted model P04117: TM-score 0.99, RMSD 0.42 Å
- 1ADL chain A against the predicted model P04117: TM-score 0.99, RMSD 0.42 Å
- 1LIE chain A against the predicted model P04117: TM-score 0.99, RMSD 0.43 Å
- 1LIE chain A against the predicted model P04117: TM-score 0.99, RMSD 0.43 Å
- 1LID chain A against the predicted model P04117: TM-score 0.99, RMSD 0.43 Å
- 1LID chain A against the predicted model P04117: TM-score 0.99, RMSD 0.43 Å
- 1LIF chain A against the predicted model P04117: TM-score 0.99, RMSD 0.44 Å
- 1LIF chain A against the predicted model P04117: TM-score 0.99, RMSD 0.44 Å
Elsewhere
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