UniProt P04039
Cytochrome c oxidase subunit 8, mitochondrial (P04039)
Cytochrome c oxidase subunit 8, mitochondrial (UniProt P04039), EC 1.9.3.1: 17 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 18 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P04039
- Protein
- Cytochrome c oxidase subunit 8, mitochondrial
- EC
- 1.9.3.1
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 18 · 8 records with a druggable one
Structures
18 records of P04039 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6GIQ | Saccharomyces cerevisiae respiratory supercomplex III2IV | electron microscopy | h | — | — |
| 6HU9 | III2-IV2 mitochondrial respiratory supercomplex from S. cerevisiae | electron microscopy | h, t | PEF | — |
| 6HU9 | III2-IV2 mitochondrial respiratory supercomplex from S. cerevisiae | electron microscopy | h, t | PEF | — |
| 6T0B | The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae | electron microscopy | h, u | PEF | — |
| 6T0B | The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae | electron microscopy | h, u | PEF | — |
| 6T15 | The III2-IV(5B)1 respiratory supercomplex from S. cerevisiae | electron microscopy | h | — | — |
| 6YMX | CIII2/CIV respiratory supercomplex from Saccharomyces cerevisiae | electron microscopy | h | CN3 | 1 (best 0.81) |
| 6YMX | CIII2/CIV respiratory supercomplex from saccharomyces cerevisiae | electron microscopy | h | CN3 | — |
| 6YMY | Cytochrome c oxidase from Saccharomyces cerevisiae | electron microscopy | h | CN3 | 2 (best 0.81) |
| 6YMY | Cytochrome C oxidase from saccharomyces cerevisiae | electron microscopy | h | CN3 | — |
| 7Z10 | Monomeric respiratory complex IV isolated from S. cerevisiae | electron microscopy | h | PEF | 2 (best 0.74) |
| 7Z10 | Monomeric respiratory complex IV isolated from S. cerevisiae | electron microscopy | h | PEF | 2 (best 0.74) |
| 8DH6 | Cryo-EM structure of Saccharomyces cerevisiae cytochrome c oxidase (Complex IV) extracted in lipid… | electron microscopy | h | PEF | 4 (best 0.79) |
| 8DH6 | Cryo-EM structure of saccharomyces cerevisiae cytochrome C oxidase (complex IV) extracted in lipid… | electron microscopy | h | PEF | — |
| 8E7S | III2IV2 respiratory supercomplex from Saccharomyces cerevisiae with 4 bound UQ6 | electron microscopy | M, m | CDL | 4 (best 0.90) |
| 8EC0 | III2IV respiratory supercomplex from Saccharomyces cerevisiae cardiolipin-lacking mutant | electron microscopy | M | — | 2 (best 0.88) |
| 9ETZ | III2IV respiratory supercomplex from Saccharomyces cerevisiae | electron microscopy | h | PEF | 1 (best 0.81) |
| P04039 | AlphaFold monomer V2.0 prediction for cytochrome C oxidase subunit 8, mitochondrial (P04039) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6T0B chain h against the predicted model P04039: TM-score 0.97, RMSD 0.39 Å
- 6T0B chain h against the predicted model P04039: TM-score 0.97, RMSD 0.39 Å
- 6HU9 chain h against the predicted model P04039: TM-score 0.96, RMSD 0.47 Å
- 6HU9 chain h against the predicted model P04039: TM-score 0.96, RMSD 0.47 Å
- 6HU9 chain t against the predicted model P04039: TM-score 0.96, RMSD 0.48 Å
- 6HU9 chain t against the predicted model P04039: TM-score 0.96, RMSD 0.48 Å
- 7Z10 chain h against the predicted model P04039: TM-score 0.95, RMSD 0.54 Å
- 7Z10 chain h against the predicted model P04039: TM-score 0.95, RMSD 0.54 Å
- 8DH6 chain h against the predicted model P04039: TM-score 0.93, RMSD 0.76 Å
- 8DH6 chain h against the predicted model P04039: TM-score 0.93, RMSD 0.76 Å
Elsewhere
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