UniProt P03962
Orotidine 5'-phosphate decarboxylase (P03962)
Orotidine 5'-phosphate decarboxylase (UniProt P03962), EC 4.1.1.23: 14 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 113 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P03962
- Protein
- Orotidine 5'-phosphate decarboxylase
- EC
- 4.1.1.23
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 113 · 15 records with a druggable one
Structures
15 records of P03962 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1DQW | Crystal structure of orotidine 5'-phosphate decarboxylase | x-ray diffraction | A, B, C, D | — | 10 (best 0.73) |
| 1DQW | Crystal structure of orotidine 5'-phosphate decarboxylase | x-ray diffraction | A, B, C, D | — | 10 (best 0.73) |
| 1DQX | Crystal structure of orotidine 5'-phosphate decarboxylase complexed to 6-hydroxyuridine… | x-ray diffraction | A, B, C, D | BMP | 4 (best 0.79) |
| 1DQX | Crystal structure of orotidine 5'-phosphate decarboxylase complexed to 6-hydroxyuridine… | x-ray diffraction | A, B, C, D | BMP | 4 (best 0.79) |
| 3GDK | Crystal structure of the orotidine 5'-monophosphate decarboxylase from Saccharomyces cerevisiae | x-ray diffraction | A, B, C, D | — | 11 (best 0.70) |
| 3GDK | Crystal structure of the orotidine 5'-monophosphate decarboxylase from saccharomyces cerevisiae | x-ray diffraction | A, B, C, D | — | 11 (best 0.70) |
| 3GDL | Crystal structure of the orotidine 5'-monophosphate decarboxylase from Saccharomyces cerevisiae… | x-ray diffraction | A, B | UP6 | 4 (best 0.75) |
| 3GDL | Crystal structure of the orotidine 5'-monophosphate decarboxylase from saccharomyces cerevisiae… | x-ray diffraction | A, B | UP6 | 4 (best 0.75) |
| 3GDM | Crystal structure of the K93R mutant of the orotidine 5'-monophosphate decarboxylase from… | x-ray diffraction | A, B | — | 5 (best 0.72) |
| 3GDM | Crystal structure of the K93R mutant of the orotidine 5'-monophosphate decarboxylase from… | x-ray diffraction | A, B | — | 5 (best 0.72) |
| 3GDR | Crystal structure of the D91N mutant of the orotidine 5'-monophosphate decarboxylase from… | x-ray diffraction | A, B, C, D | — | 11 (best 0.68) |
| 3GDR | Crystal structure of the D91N mutant of the orotidine 5'-monophosphate decarboxylase from… | x-ray diffraction | A, B, C, D | — | 11 (best 0.68) |
| 3GDT | Crystal structure of the D91N mutant of the orotidine 5'-monophosphate decarboxylase from… | x-ray diffraction | A, B, C, D | UP6 | 11 (best 0.68) |
| 3GDT | Crystal structure of the D91N mutant of the orotidine 5'-monophosphate decarboxylase from… | x-ray diffraction | A, B, C, D | UP6 | 11 (best 0.68) |
| P03962 | AlphaFold monomer V2.0 prediction for orotidine 5'-phosphate decarboxylase (P03962) | predicted | A | — | 1 (best 0.56) |
Ligands
Experiment against prediction
- 3GDL chain A against the predicted model P03962: TM-score 0.99, RMSD 0.45 Å
- 3GDL chain A against the predicted model P03962: TM-score 0.99, RMSD 0.45 Å
- 1DQX chain A against the predicted model P03962: TM-score 0.98, RMSD 0.81 Å
- 1DQX chain A against the predicted model P03962: TM-score 0.98, RMSD 0.81 Å
- 3GDK chain C against the predicted model P03962: TM-score 0.98, RMSD 0.77 Å
- 3GDK chain C against the predicted model P03962: TM-score 0.98, RMSD 0.77 Å
- 3GDR chain C against the predicted model P03962: TM-score 0.98, RMSD 1.07 Å
- 3GDR chain C against the predicted model P03962: TM-score 0.98, RMSD 1.07 Å
- 3GDT chain C against the predicted model P03962: TM-score 0.98, RMSD 1.07 Å
- 3GDT chain C against the predicted model P03962: TM-score 0.98, RMSD 1.07 Å
Elsewhere
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