UniProt P03856
Replication initiation protein (P03856)
Replication initiation protein (UniProt P03856): 14 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 37 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P03856
- Protein
- Replication initiation protein
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 37 · 8 records with a druggable one
Structures
15 records of P03856 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1REP | Crystal structure of replication initiator protein REPE54 of mini-F plasmid complexed with an… | x-ray diffraction | C | — | — |
| 1REP | Crystal structure of replication initiator protein REPE54 of mini-F plasmid complexed with an… | x-ray diffraction | C | — | — |
| 2Z9O | Crystal structure of the dimeric form of RepE in complex with the repE operator DNA | x-ray diffraction | A, B | — | — |
| 2Z9O | Crystal structure of the dimeric form of repe in complex with the repe operator DNA | x-ray diffraction | A, B | — | — |
| 7RVA | Updated crystal structure of replication initiator protein REPE54. | x-ray diffraction | C | MG | — |
| 7U7O | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical… | x-ray diffraction | C | MG | — |
| 7UFX | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and… | x-ray diffraction | C | MG | 5 (best 0.61) |
| 7UR0 | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and… | x-ray diffraction | C | MG | 5 (best 0.59) |
| 8D86 | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical… | x-ray diffraction | C | NT, MG | 5 (best 0.63) |
| 8D8M | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical… | x-ray diffraction | C | CA | 5 (best 0.62) |
| 8TIW | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical… | x-ray diffraction | C | MG | 4 (best 0.58) |
| 8TIY | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical… | x-ray diffraction | C | MG | 5 (best 0.61) |
| 8TIZ | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical… | x-ray diffraction | C | MG | 3 (best 0.61) |
| 8TJ1 | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical… | x-ray diffraction | C | MG | 4 (best 0.62) |
| P03856 | AlphaFold monomer V2.0 prediction for replication initiation protein (P03856) | predicted | A | — | 1 (best 0.45) |
Ligands
Experiment against prediction
- 1REP chain C against the predicted model P03856: TM-score 0.99, RMSD 0.45 Å
- 1REP chain C against the predicted model P03856: TM-score 0.99, RMSD 0.45 Å
- 7UR0 chain C against the predicted model P03856: TM-score 0.99, RMSD 0.58 Å
- 8TIW chain C against the predicted model P03856: TM-score 0.99, RMSD 0.57 Å
- 7UFX chain C against the predicted model P03856: TM-score 0.99, RMSD 0.60 Å
- 8TIY chain C against the predicted model P03856: TM-score 0.99, RMSD 0.59 Å
- 8TIZ chain C against the predicted model P03856: TM-score 0.99, RMSD 0.60 Å
- 8TJ1 chain C against the predicted model P03856: TM-score 0.99, RMSD 0.60 Å
- 8D8M chain C against the predicted model P03856: TM-score 0.99, RMSD 0.63 Å
- 7U7O chain C against the predicted model P03856: TM-score 0.99, RMSD 0.68 Å
Elsewhere
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