GL1X · GenesisL1 explorer

MolNFT v1 · #339269 · protein

AlphaFold monomer V2.0 prediction for replication initiation protein (P03856)

P03856: “AlphaFold monomer V2.0 prediction for replication initiation protein (P03856)”. 1 pocket (best druggability 0.45). MolNFT v1 #339269 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P03856
Type
protein
Length
251 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x5e58272ea25a05e06901A2eAe9f63939b344e0c6
Molecule
Replication initiation protein
UniProt
P03856
Pockets
1 · best druggability 0.45

Structure

1 distinct chain · 43% helix, 28% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AReplication initiation proteinprotein25143% helix, 28% strandP03856

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11690.450.7524empty

Compared structures

  • 8AAN · The nucleoprotein complex of Rep protein with iteron containing dsDNA and DUE ssDNA. · an experimental structure of the same protein · chain A against A, TM-score 0.87
  • 7RVA · Updated Crystal Structure of Replication Initiator Protein REPE54. · an experimental structure of the same protein · chain A against C, TM-score 0.87
  • 7RVA · Updated crystal structure of replication initiator protein REPE54. · an experimental structure of the same protein · chain A against C, TM-score 0.87
  • 8AC8 · The nucleoprotein complex of Rep protein with DUE ssDNA · an experimental structure of the same protein · chain A against A, TM-score 0.85
  • 7U7O · Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and… · an experimental structure of the same protein · chain A against C, TM-score 0.85
  • 1REP · Crystal structure of replication initiator protein REPE54 of mini-F plasmid complexed… · an experimental structure of the same protein · chain A against C, TM-score 0.85
  • 1REP · Crystal structure of replication initiator protein REPE54 of mini-F plasmid complexed… · an experimental structure of the same protein · chain A against C, TM-score 0.85
  • 8TIP · Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and… · an experimental structure of the same protein · chain A against C, TM-score 0.85
  • 7UOG · Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and… · an experimental structure of the same protein · chain A against C, TM-score 0.84
  • 8D86 · Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and… · an experimental structure of the same protein · chain A against C, TM-score 0.84
  • 7UV6 · Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and… · an experimental structure of the same protein · chain A against C, TM-score 0.84

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