UniProt P02730
Band 3 anion transport protein (P02730)
Band 3 anion transport protein (UniProt P02730): 79 experimental structures and 1 predicted model on GenesisL1, 14 ligands bound, 403 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02730
- Protein
- Band 3 anion transport protein
- Experimental structures
- 79
- Predicted models
- 1
- Ligands
- 14
- Pockets
- 403 · 33 records with a druggable one
Structures
80 records of P02730 in the MolNFT archive: 79 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BH7 | A low energy structure for the final cytoplasmic loop of band 3, NMR, minimized average structure | solution nmr | A | — | — |
| 1BH7 | A low energy structure for the final cytoplasmic loop of band 3, NMR, minimized average structure | solution nmr | A | — | — |
| 1BNX | Structural studies on the effects of the deletion in the red cell anion exchanger (BAND3, AE1)… | solution nmr | A | — | — |
| 1BNX | Structural studies on the effects of the deletion in the red cell anion exchanger (BAND3, AE1)… | solution nmr | A | — | — |
| 1BTQ | The solution structures of the first and second transmembrane-spanning segments of band 3 | solution nmr | A | — | — |
| 1BTQ | The solution structures of the first and second transmembrane-spanning segments of band 3 | solution nmr | A | — | — |
| 1BTR | The solution structures of the first and second transmembrane-spanning segments of band 3 | solution nmr | A | — | — |
| 1BTR | The solution structures of the first and second transmembrane-spanning segments of band 3 | solution nmr | A | — | — |
| 1BTS | The solution structures of the first and second transmembrane-spanning segments of band 3 | solution nmr | A | — | — |
| 1BTS | The solution structures of the first and second transmembrane-spanning segments of band 3 | solution nmr | A | — | — |
| 1BTT | The solution structures of the first and second transmembrane-spanning segments of band 3 | solution nmr | A | — | — |
| 1BTT | The solution structures of the first and second transmembrane-spanning segments of band 3 | solution nmr | A | — | — |
| 1BZK | Structural studies on the effects of the deletion in the red cell anion exchanger (BAND3, AE1)… | solution nmr | A | — | — |
| 1BZK | Structural studies on the effects of the deletion in the red cell anion exchanger (BAND3, AE1)… | solution nmr | A | — | — |
| 1HYN | Crystal structure of the cytoplasmic domain of human erythrocyte band-3 protein | x-ray diffraction | P, Q, R, S | — | — |
| 1HYN | Crystal structure of the cytoplasmic domain of human erythrocyte band- 3 protein | x-ray diffraction | P, Q, R, S | — | — |
| 2BTA | NMR study of N-terminal human band 3 peptide, residues 1-15 | solution nmr | A | — | — |
| 2BTA | NMR study of N-terminal human band 3 peptide, residues 1-15 | solution nmr | A | — | — |
| 2BTB | NMR study of N-terminal human band 3 peptide, residues 1-15 | solution nmr | A | — | — |
| 2BTB | NMR study of N-terminal human band 3 peptide, residues 1-15 | solution nmr | A | — | — |
| 3BTB | NMR solution structure of a band 3 peptide inhibitor bound to glyceraldehyde-3-phosphate… | solution nmr | A | — | — |
| 3BTB | NMR solution structure of a band 3 peptide inhibitor bound to glyceraldehyde-3-phosphate… | solution nmr | A | — | — |
| 4KY9 | Structural and Functional Analysis of a Putative Substrate Access Tunnel in the Cytosolic Domain of… | x-ray diffraction | A, P | — | — |
| 4KY9 | Structural and functional analysis of a putative substrate access tunnel in the cytosolic domain of… | x-ray diffraction | A, P | — | — |
| 4YZF | Crystal structure of the anion exchanger domain of human erythrocyte Band 3 | x-ray diffraction | A, B, C, D | 4KU | 16 (best 0.75) |
| 4YZF | Crystal structure of the anion exchanger domain of human erythrocyte band 3 | x-ray diffraction | A, B, C, D | — | — |
| 7TVZ | Cryo-EM structure of human band 3-protein 4.2 complex in diagonal conformation | electron microscopy | A, B | NAG, CLR | 16 (best 0.86) |
| 7TVZ | Cryo-EM structure of human band 3-protein 4.2 complex in diagonal conformation | electron microscopy | A, B | NAG, CLR | — |
| 7TW0 | Cryo-EM structure of human band 3-protein 4.2 complex in vertical conformation | electron microscopy | B, A | NAG | 16 (best 0.87) |
| 7TW0 | Cryo-EM structure of human band 3-protein 4.2 complex in vertical conformation | electron microscopy | B, A | NAG | — |
| 7TW1 | Cryo-EM structure of human band 3-protein 4.2 complex (B2P2vertical) | electron microscopy | B, A | — | 12 (best 0.88) |
| 7TW1 | Cryo-EM structure of human band 3-protein 4.2 complex (B2P2VERTICAL) | electron microscopy | B, A | — | — |
| 7TW2 | Cryo-EM structure of human band 3 dimer from red blood cell | electron microscopy | B, A | NAG | 20 (best 0.80) |
| 7TW3 | Cryo-EM structure of human ankyrin complex (B2P1A1) from red blood cell | electron microscopy | A, B | — | — |
| 7TW5 | Cryo-EM structure of human ankyrin complex (B2P1A2) from red blood cell | electron microscopy | A, B | — | 14 (best 0.87) |
| 7TW5 | Cryo-EM structure of human ankyrin complex (B2P1A2) from red blood cell | electron microscopy | A, B | — | — |
| 7TW6 | Cryo-EM structure of human ankyrin complex (B4P1A1) from red blood cell | electron microscopy | A, B, K, J | — | — |
| 7TY4 | Cryo-EM structure of human Anion Exchanger 1 | electron microscopy | A, B | NAG, CLR, PC1, Y01 | 13 (best 0.75) |
| 7TY6 | Cryo-EM structure of human Anion Exchanger 1 bound to… | electron microscopy | A, B | NAG, CLR, PC1, 4DS | 16 (best 0.78) |
| 7TY7 | Cryo-EM structure of human Anion Exchanger 1 bound to Bicarbonate | electron microscopy | A, B | NAG, BCT, CLR, PC1 | 13 (best 0.76) |
| 7TY8 | Cryo-EM structure of human Anion Exchanger 1 bound to Niflumic Acid | electron microscopy | A, B | NAG, CLR, PC1, NFL | 12 (best 0.77) |
| 7TYA | Cryo-EM structure of human Anion Exchanger 1 modified with Diethyl Pyrocarbonate (DEPC) | electron microscopy | A, B | NAG, CLR, PC1 | 15 (best 0.73) |
| 7UZ3 | Band 3-Glycophorin A complex, outward facing | electron microscopy | C, E | NAG, BMA, FUC, CLR, PLC, PIO | 15 (best 0.77) |
| 7UZ3 | Band 3-glycophorin a complex, outward facing | electron microscopy | C, E | NAG, BMA, FUC, CLR, PLC, PIO | — |
| 7UZU | Ankyrin-1 (N-terminal region of membrane binding domain, local refinement from consensus… | electron microscopy | W | — | 1 (best 0.52) |
| 7UZU | Ankyrin-1 (N-terminal region of membrane binding domain, local refinement from consensus… | electron microscopy | W | — | — |
| 7UZV | Cytoplasmic domains of Band 3-I (local refinement from consensus reconstruction of ankyrin… | electron microscopy | E, C | — | 6 (best 0.74) |
| 7UZV | Cytoplasmic domains of band 3-I (local refinement from consensus reconstruction of ankyrin… | electron microscopy | E, C | — | — |
| 7V07 | Band 3-I-TM local refinement from erythrocyte ankyrin-1 complex consensus reconstruction | electron microscopy | C, E | NAG, FUC, BMA, CLR, PLC, PIO | 15 (best 0.77) |
| 7V07 | Band 3-I-tm local refinement from erythrocyte ankyrin-1 complex consensus reconstruction | electron microscopy | C, E | NAG, FUC, BMA, CLR, PLC, PIO | — |
| 7V0K | Consensus refinement of human erythrocyte ankyrin-1 complex (Composite map) | electron microscopy | W, O, P | CLR, NAG, PLC, PIO | 12 (best 0.85) |
| 7V0M | Local refinement of ankyrin-1 (N-terminal half), class 1 of erythrocyte ankyrin-1 complex | electron microscopy | W | — | — |
| 7V0T | Local refinement of Band 3-I cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex | electron microscopy | E, C | — | 5 (best 0.75) |
| 7V0U | Local refinement of Band 3-II cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex | electron microscopy | F, D | — | 4 (best 0.74) |
| 7V0U | Local refinement of band 3-II cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex | electron microscopy | F, D | — | — |
| 7V0Y | Local refinement of Band 3-III cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex | electron microscopy | E, C | — | 4 (best 0.74) |
| 7V0Y | Local refinement of band 3-III cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex | electron microscopy | E, C | — | — |
| 7V19 | Local refinement of Band 3-II transmembrane domains, class 1 of erythrocyte ankyrin-1 complex | electron microscopy | C, E | NAG, CLR, PIO | 16 (best 0.78) |
| 7V19 | Local refinement of band 3-II transmembrane domains, class 1 of erythrocyte ankyrin-1 complex | electron microscopy | C, E | NAG, CLR, PIO | — |
| 8CRQ | Local refinement of Band 3-I transmembrane domains, class 1 of erythrocyte ankyrin-1 complex | electron microscopy | C, E | NAG, CLR, PIO | 16 (best 0.76) |
20 records more on the page itself.
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 33 records
- CLR · Cholesterol · in 27 records
- PIO · [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2, 3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate · in 19 records
- PLC · Diundecyl phosphatidyl choline · in 8 records
- PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · in 7 records
- BMA · beta-D-mannopyranose · in 4 records
- FUC · alpha-L-fucopyranose · in 4 records
- 4DS · 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid · in 2 records
- CO3 · Carbonate ion · in 2 records
- Y01 · Cholesterol hemisuccinate · in 2 records
- 4KU · 2,2'-ethane-1,2-diylbis{5-[(sulfanylmethyl)amino]benzenesulfonic acid} · in 1 record
- BCT · Bicarbonate ion · in 1 record
- H9F · 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl) amino]ethanol · in 1 record
- NFL · 2-{[3-(trifluoromethyl)phenyl]amino}nicotinic acid · in 1 record
Experiment against prediction
- 8T44 chain B against the predicted model P02730: TM-score 0.99, RMSD 0.78 Å
- 7TY4 chain B against the predicted model P02730: TM-score 0.99, RMSD 0.83 Å
- 7TY4 chain A against the predicted model P02730: TM-score 0.99, RMSD 0.84 Å
- 8T47 chain B against the predicted model P02730: TM-score 0.99, RMSD 0.82 Å
- 8T6U chain B against the predicted model P02730: TM-score 0.99, RMSD 0.84 Å
- 7TYA chain B against the predicted model P02730: TM-score 0.99, RMSD 0.85 Å
- 7TYA chain A against the predicted model P02730: TM-score 0.99, RMSD 0.85 Å
- 8T6U chain A against the predicted model P02730: TM-score 0.99, RMSD 0.84 Å
- 8T47 chain A against the predicted model P02730: TM-score 0.99, RMSD 0.84 Å
- 8T6V chain B against the predicted model P02730: TM-score 0.99, RMSD 0.85 Å
Elsewhere
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