UniProt P01900
H-2 class I histocompatibility antigen, D-D alpha chain (P01900)
H-2 class I histocompatibility antigen, D-D alpha chain (UniProt P01900): 34 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 52 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P01900
- Protein
- H-2 class I histocompatibility antigen, D-D alpha chain
- Experimental structures
- 34
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 52 · 8 records with a druggable one
Structures
35 records of P01900 in the MolNFT archive: 34 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BII | The crystal structure of H-2DD MHC class I in complex with the HIV-1 derived peptide P18-110 | x-ray diffraction | A | — | — |
| 1BII | The crystal structure of H-2DD MHC class I in complex with the HIV-1 derived peptide P18-110 | x-ray diffraction | A | — | — |
| 1DDH | MHC class I H-2DD heavy chain complexed with beta-2 microglobulin and an immunodominant peptide… | x-ray diffraction | A | — | — |
| 1DDH | MHC class I H-2DD heavy chain complexed with beta-2 microglobulin and an immunodominant peptide… | x-ray diffraction | A | — | — |
| 1QO3 | Complex between NK cell receptor Ly49A and its MHC class I ligand H-2Dd | x-ray diffraction | A | — | — |
| 1QO3 | Complex between nk cell receptor LY49A and its MHC class I ligand H-2DD | x-ray diffraction | A | — | — |
| 3DMM | Crystal structure of the CD8 alpha beta/H-2Dd complex | x-ray diffraction | A | — | — |
| 3DMM | Crystal structure of the CD8 alpha BETA/H-2DD complex | x-ray diffraction | A | — | — |
| 3E6F | MHC CLASS I H-2Dd Heavy chain complexed with Beta-2 Microglobulin and a variant peptide, PA9, from… | x-ray diffraction | A | — | — |
| 3E6F | MHC class I H-2DD heavy chain complexed with beta-2 microglobulin and a variant peptide, PA9, from… | x-ray diffraction | A | — | — |
| 3E6H | MHC CLASS I H-2Dd heavy chain complexed with Beta-2 Microglobulin and a variant peptide, PI10, from… | x-ray diffraction | A | — | — |
| 3E6H | MHC class I H-2DD heavy chain complexed with beta-2 microglobulin and a variant peptide, PI10, from… | x-ray diffraction | A | — | — |
| 3ECB | Crystal structure of mouse H-2Dd in complex with peptide P18-I10 derived from human… | x-ray diffraction | A | — | — |
| 3ECB | Crystal structure of mouse H-2DD in complex with peptide P18-I10 derived from human… | x-ray diffraction | A | — | — |
| 5IVX | Crystal Structure of B4.2.3 T-Cell Receptor and H2-Dd P18-I10 Complex | x-ray diffraction | A | — | 7 (best 0.64) |
| 5IVX | Crystal structure of B4.2.3 T-cell receptor and H2-dd P18-I10 complex | x-ray diffraction | A | — | — |
| 5KD4 | Crystal structure of murine MHC-I H-2DD in complex with murine BETA2- microglobulin and a variant… | x-ray diffraction | A, C | — | — |
| 5KD7 | Crystal Structure of Murine MHC-I H-2Dd in complex with Murine Beta2-Microglobulin and a Variant of… | x-ray diffraction | A, C, F, I | — | — |
| 5KD7 | Crystal structure of murine MHC-I H-2DD in complex with murine BETA2- microglobulin and a variant… | x-ray diffraction | A, C, F, I | — | — |
| 5T7G | Crystal structure of murine MHC-I H-2DD in complex with murine BETA2- microglobulin and a variant… | x-ray diffraction | A, C | — | — |
| 5WER | Crystal structure of tapbpr and H2-dd complex | x-ray diffraction | A, D, G, J | — | — |
| 5WES | Crystal Structure H2-Dd with disulfide-linked 5mer peptide | x-ray diffraction | A | — | 5 (best 0.64) |
| 5WES | Crystal structure H2-dd with disulfide-linked 5MER peptide | x-ray diffraction | A | — | — |
| 5WET | Crystal Structure of H2-Dd with disulfide-linked 6mer peptide | x-ray diffraction | A | — | 7 (best 0.63) |
| 5WET | Crystal structure of H2-dd with disulfide-linked 6MER peptide | x-ray diffraction | A | — | — |
| 5WEU | Crystal structure of H2-dd with disulfide-linked 10MER peptide | x-ray diffraction | A | — | — |
| 6NPR | Crystal structure of H-2DD with C84-C139 disulfide in complex with GP120 derived peptide P18-I10 | x-ray diffraction | A, C | — | — |
| 8D5E | The complex of GTF2B peptide tgaasfdef presented by H2-kd | x-ray diffraction | A | — | — |
| 8D5F | The complex of Gtf2b neoantigen TGAARFDEF Presented by H2-Dd | x-ray diffraction | A | — | 4 (best 0.66) |
| 8D5F | The complex of GTF2B neoantigen tgaarfdef presented by H2-kd | x-ray diffraction | A | — | — |
| 8FHL | Structure of pyruvate dehydrogenase phosphatase regulatory subunit neoepitope presented by H2-Dd | x-ray diffraction | A | NA | 4 (best 0.67) |
| 8FHU | Structure of Pyruvate dehydrogenase phosphatase regulatory subunit epitope presented by H2-Dd | x-ray diffraction | A, D | K | 8 (best 0.74) |
| 8TQ8 | Crystal structure of Fab.34.5.8 in complex with MHC-I (H2-Dd) | x-ray diffraction | A, C | — | 11 (best 0.71) |
| 8TQ9 | Crystal structure of Fab.S19.8 in complex with MHC-I (H2-Dd) | x-ray diffraction | A | SO4 | 6 (best 0.67) |
| P01900 | AlphaFold monomer V2.0 prediction for H-2 class I histocompatibility antigen, D-D alpha chain… | predicted | A | — | — |
Ligands
Experiment against prediction
- 5T7G chain A against the predicted model P01900: TM-score 0.99, RMSD 0.56 Å
- 8TQ8 chain A against the predicted model P01900: TM-score 0.99, RMSD 0.60 Å
- 8TQ8 chain C against the predicted model P01900: TM-score 0.99, RMSD 0.67 Å
- 8TQ9 chain A against the predicted model P01900: TM-score 0.98, RMSD 0.83 Å
- 8FHU chain D against the predicted model P01900: TM-score 0.98, RMSD 0.89 Å
- 1BII chain A against the predicted model P01900: TM-score 0.98, RMSD 0.94 Å
- 1BII chain A against the predicted model P01900: TM-score 0.98, RMSD 0.94 Å
- 6NPR chain A against the predicted model P01900: TM-score 0.98, RMSD 1.00 Å
- 3E6F chain A against the predicted model P01900: TM-score 0.97, RMSD 1.03 Å
- 3E6F chain A against the predicted model P01900: TM-score 0.97, RMSD 1.03 Å
Elsewhere
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