UniProt P01591
Immunoglobulin J chain (P01591)
Immunoglobulin J chain (UniProt P01591): 26 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 80 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01591
- Protein
- Immunoglobulin J chain
- Experimental structures
- 26
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 80 · 17 records with a druggable one
Structures
27 records of P01591 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6KXS | Cryo-EM structure of human IgM-Fc in complex with the J chain and the ectodomain of pIgR | electron microscopy | J | NAG | 3 (best 0.89) |
| 6KXS | Cryo-EM structure of human IgM-Fc in complex with the J chain and the ectodomain of pigr | electron microscopy | J | NAG | — |
| 6LX3 | Cryo-EM structure of human secretory immunoglobulin A | electron microscopy | J | — | 7 (best 0.84) |
| 6LX3 | Cryo-EM structure of human secretory immunoglobulin a | electron microscopy | J | — | — |
| 6LXW | Cryo-EM structure of human secretory immunoglobulin A in complex with the N-terminal domain of SpsA | electron microscopy | J | — | 8 (best 0.83) |
| 6LXW | Cryo-EM structure of human secretory immunoglobulin a in complex with the N-terminal domain of spsa | electron microscopy | J | — | — |
| 6UE7 | Structure of dimeric sIgA complex | electron microscopy | D | NAG | 7 (best 0.84) |
| 6UE7 | Structure of dimeric siga complex | electron microscopy | D | NAG | — |
| 6UE8 | Structure of tetrameric siga complex (class 1) | electron microscopy | D | NAG | — |
| 6UE9 | Structure of tetrameric siga complex (class 2) | electron microscopy | D | NAG | — |
| 6UEA | Structure of pentameric siga complex | electron microscopy | D | NAG | — |
| 7K0C | Structure of Secretory IgM Core | electron microscopy | D | NAG | 3 (best 0.88) |
| 7K0C | Structure of secretory IgM core | electron microscopy | D | NAG | — |
| 7Y09 | Cryo-EM structure of human IgM-Fc in complex with the J chain and the DBL domain of DBLMSP | electron microscopy | J | NAG | 3 (best 0.87) |
| 7Y0H | Cryo-EM structure of human IgM-Fc in complex with the J chain and the P. falciparum VAR2CSA FCR3 | electron microscopy | J | NAG | 3 (best 0.86) |
| 7YG2 | Cryo-EM structure of human IgM-Fc in complex with the J chain and the DBL domain of DBLMSP2 | electron microscopy | J | NAG | 3 (best 0.87) |
| 7YSG | Cryo-EM structure of human FcmR bound to sIgM | electron microscopy | J | NAG | — |
| 7YTC | Cryo-EM structure of human FcmR bound to IgM-Fc/J | electron microscopy | J | NAG | 3 (best 0.87) |
| 7YTD | Cryo-EM structure of four human FcmR bound to IgM-Fc/J | electron microscopy | J | NAG | 2 (best 0.85) |
| 8GZN | IgM-var2CSA complex | electron microscopy | J | — | 3 (best 0.84) |
| 8R83 | pentameric IgMFc-AIM complex global refinement | electron microscopy | J | NAG, CA | 3 (best 0.85) |
| 8R84 | pentameric IgMFc-AIM complex focused refinement | electron microscopy | J | NAG, CA | 8 (best 0.82) |
| 8SKU | Structure of human SIgA1 in complex with human CD89 (FcaR1) | electron microscopy | J | NAG | 8 (best 0.84) |
| 8SKV | Structure of human SIgA1 in complex with Streptococcus pyogenes protein M4 (Arp4) | electron microscopy | J | NAG | 7 (best 0.86) |
| 8WYR | Cryo-EM structure of human CD5L bound to IgM-Fc/J | electron microscopy | J | NAG, CA | 7 (best 0.86) |
| 9ARV | CryoEM structure of AMETA-A3 | electron microscopy | J | — | 2 (best 0.80) |
| P01591 | AlphaFold monomer V2.0 prediction for immunoglobulin J chain (P01591) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6LX3 chain J against the predicted model P01591: TM-score 0.95, RMSD 1.16 Å
- 6LX3 chain J against the predicted model P01591: TM-score 0.95, RMSD 1.16 Å
- 6UE8 chain D against the predicted model P01591: TM-score 0.94, RMSD 1.21 Å
- 6LXW chain J against the predicted model P01591: TM-score 0.94, RMSD 1.19 Å
- 6LXW chain J against the predicted model P01591: TM-score 0.94, RMSD 1.19 Å
- 6UE9 chain D against the predicted model P01591: TM-score 0.94, RMSD 1.21 Å
- 6UE7 chain D against the predicted model P01591: TM-score 0.93, RMSD 1.21 Å
- 6UE7 chain D against the predicted model P01591: TM-score 0.93, RMSD 1.21 Å
- 8SKU chain J against the predicted model P01591: TM-score 0.93, RMSD 1.24 Å
- 6UEA chain D against the predicted model P01591: TM-score 0.93, RMSD 1.26 Å
Elsewhere
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