UniProt P01222
Thyrotropin subunit beta (P01222)
Thyrotropin subunit beta (UniProt P01222): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01222
- Protein
- Thyrotropin subunit beta
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 10 · 2 records with a druggable one
Structures
6 records of P01222 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7T9I | Native human TSH bound to human Thyrotropin receptor in complex with miniGs399 (composite structure) | electron microscopy | B | NAG | 5 (best 0.79) |
| 7T9I | Native human tsh bound to human thyrotropin receptor in complex with MINIGS399 (composite structure) | electron microscopy | B | NAG | — |
| 7UTZ | Human thyrotropin analog TR1402 bound to human thyrotropin receptor in complex with MINIGS399… | electron microscopy | B | NAG | — |
| 7XW5 | TSHR-thyroid stimulating hormone-Gs-ML109 complex | electron microscopy | Y | NAG | 4 (best 0.70) |
| 7XW5 | Tshr-thyroid stimulating hormone-gs-ML109 complex | electron microscopy | Y | NAG | — |
| P01222 | AlphaFold monomer V2.0 prediction for thyrotropin subunit beta (P01222) | predicted | A | — | 1 (best 0.48) |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 5 records
Experiment against prediction
- 7UTZ chain B against the predicted model P01222: TM-score 0.92, RMSD 1.34 Å
- 7T9I chain B against the predicted model P01222: TM-score 0.91, RMSD 1.45 Å
- 7T9I chain B against the predicted model P01222: TM-score 0.91, RMSD 1.45 Å
- 7XW5 chain Y against the predicted model P01222: TM-score 0.89, RMSD 1.44 Å
- 7XW5 chain Y against the predicted model P01222: TM-score 0.89, RMSD 1.44 Å
Elsewhere
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