UniProt P00846
ATP synthase subunit a (P00846)
ATP synthase subunit a (UniProt P00846): 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 47 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P00846
- Protein
- ATP synthase subunit a
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 47 · 8 records with a druggable one
Structures
9 records of P00846 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8H9F | Human ATP synthase state 1 subregion 3 | electron microscopy | N | CDL, 3PH | 12 (best 0.78) |
| 8H9J | Human ATP synthase state2 subregion 3 | electron microscopy | N | — | 10 (best 0.77) |
| 8H9M | Human ATP synthase state 3a subregion 3 | electron microscopy | N | — | 8 (best 0.82) |
| 8H9S | Human ATP synthase state 1 (combined) | electron microscopy | N | CDL, 3PH | 4 (best 0.77) |
| 8H9T | Human ATP synthase state 2 (combined) | electron microscopy | N | — | 3 (best 0.77) |
| 8H9U | Human ATP synthase state 3a (combined) | electron microscopy | N | — | 3 (best 0.82) |
| 8H9V | Human ATP synthase state 3b (combined) | electron microscopy | N | — | 5 (best 0.76) |
| 8KI3 | Structure of the human ATP synthase bound to bedaquiline (composite) | electron microscopy | N | BQ1 | 2 (best 0.76) |
| P00846 | AlphaFold monomer V2.0 prediction for ATP synthase subunit a (P00846) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8H9T chain N against the predicted model P00846: TM-score 0.98, RMSD 0.90 Å
- 8H9J chain N against the predicted model P00846: TM-score 0.98, RMSD 0.92 Å
- 8H9V chain N against the predicted model P00846: TM-score 0.98, RMSD 0.91 Å
- 8H9M chain N against the predicted model P00846: TM-score 0.97, RMSD 0.96 Å
- 8H9U chain N against the predicted model P00846: TM-score 0.97, RMSD 0.95 Å
- 8H9F chain N against the predicted model P00846: TM-score 0.97, RMSD 1.07 Å
- 8H9S chain N against the predicted model P00846: TM-score 0.97, RMSD 1.07 Å
- 8KI3 chain N against the predicted model P00846: TM-score 0.97, RMSD 1.07 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.