UniProt P00766
gamma-chymotrypsin (P00766)
gamma-chymotrypsin (UniProt P00766), EC 3.4.21.1: 157 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P00766
- Protein
- gamma-chymotrypsin
- EC
- 3.4.21.1
- Experimental structures
- 157
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 13 · 2 records with a druggable one
Structures
158 records of P00766 in the MolNFT archive: 157 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AB9 | Crystal structure of bovine gamma-chymotrypsin | x-ray diffraction | A, B, C | — | — |
| 1AB9 | Crystal structure of bovine gamma-chymotrypsin | x-ray diffraction | A, B, C | — | — |
| 1ACB | Crystal and molecular structure of the bovine alpha-chymotrypsin-eglin C complex at 2.0 ångströms… | x-ray diffraction | E | — | — |
| 1ACB | Crystal and molecular structure of the bovine alpha-chymotrypsin-eglin C complex at 2.0 ångströms… | x-ray diffraction | E | — | — |
| 1AFQ | Crystal structure of bovine gamma-chymotrypsin complexed with a synthetic inhibitor | x-ray diffraction | A, B, C | — | — |
| 1AFQ | Crystal structure of bovine gamma-chymotrypsin complexed with a synthetic inhibitor | x-ray diffraction | A, B, C | — | — |
| 1CA0 | Bovine chymotrypsin complexed to appi | x-ray diffraction | A, B, C, F, G, H | — | — |
| 1CA0 | Bovine chymotrypsin complexed to appi | x-ray diffraction | A, B, C, F, G, H | — | — |
| 1CBW | Bovine chymotrypsin complexed to bpti | x-ray diffraction | B, C, G, H | — | — |
| 1CBW | Bovine chymotrypsin complexed to bpti | x-ray diffraction | B, C, G, H | — | — |
| 1CGI | Three-dimensional structure of the complexes between bovine CHYMOTRYPSINOGEN*A and two recombinant… | x-ray diffraction | E | — | — |
| 1CGI | Three-dimensional structure of the complexes between bovine CHYMOTRYPSINOGEN*A and two recombinant… | x-ray diffraction | E | — | — |
| 1CGJ | Three-dimensional structure of the complexes between bovine CHYMOTRYPSINOGEN*A and two recombinant… | x-ray diffraction | E | — | — |
| 1CGJ | Three-dimensional structure of the complexes between bovine CHYMOTRYPSINOGEN*A and two recombinant… | x-ray diffraction | E | — | — |
| 1CHG | CHYMOTRYPSINOGEN,2.5 ångströms crystal structure, comparison with alpha-CHYMOTRYPSIN,AND… | x-ray diffraction | A | — | — |
| 1CHG | CHYMOTRYPSINOGEN,2.5 ångströms crystal structure, comparison with alpha-CHYMOTRYPSIN,AND… | x-ray diffraction | A | — | — |
| 1CHO | Crystal and molecular structures of the complex of alpha-*chymotrypsin with its inhibitor turkey… | x-ray diffraction | E, F, G | — | — |
| 1CHO | Crystal and molecular structures of the complex of alpha-*chymotrypsin with its inhibitor turkey… | x-ray diffraction | E, F, G | — | — |
| 1DLK | Crystal structure analysis of delta-chymotrypsin bound to a peptidyl chloromethyl ketone inhibitor | x-ray diffraction | A, B, C, D | — | — |
| 1DLK | Crystal structure analysis of delta-chymotrypsin bound to a peptidyl chloromethyl ketone inhibitor | x-ray diffraction | A, B, C, D | — | — |
| 1EX3 | Crystal structure of bovine chymotrypsinogen a (tetragonal) | x-ray diffraction | A | — | — |
| 1EX3 | Crystal structure of bovine chymotrypsinogen a (tetragonal) | x-ray diffraction | A | — | — |
| 1GCD | Refined crystal structure of "aged" and "non-aged" organophosphoryl conjugates of gamma-chymotrypsin | x-ray diffraction | A | — | — |
| 1GCD | Refined crystal structure of "aged" and "non-aged" organophosphoryl conjugates of gamma-chymotrypsin | x-ray diffraction | A | — | — |
| 1GCT | Is gamma-chymotrypsin a tetrapeptide acyl-enzyme adduct of gamma-chymotrypsin? | x-ray diffraction | A, B, C | — | — |
| 1GCT | Is gamma-chymotrypsin a tetrapeptide acyl-enzyme adduct of gamma- chymotrypsin? | x-ray diffraction | A, B, C | — | — |
| 1GG6 | Crystal structure of gamma chymotrypsin with N-acetyl-phenylalanine trifluoromethyl ketone bound at… | x-ray diffraction | A, B, C | — | — |
| 1GG6 | Crystal structure of gamma chymotrypsin with N-acetyl-phenylalanine trifluoromethyl ketone bound at… | x-ray diffraction | A, B, C | — | — |
| 1GGD | Crystal structure of gamma chymotrypsin with N-acetyl-leucil-phenylalanine aldehyde bound at the… | x-ray diffraction | A, B, C | — | — |
| 1GGD | Crystal structure of gamma chymotrypsin with N-acetyl-leucil- phenylalanine aldehyde bound at the… | x-ray diffraction | A, B, C | — | — |
| 1GHA | A second active site in chymotrypsin? the X-ray crystal structure of N-acetyl-D-tryptophan bound to… | x-ray diffraction | E, F, G | — | — |
| 1GHA | A second active site in chymotrypsin? the X-ray crystal structure of N-acetyl-D-tryptophan bound to… | x-ray diffraction | E, F, G | — | — |
| 1GHB | A second active site in chymotrypsin? the X-ray crystal structure of N-acetyl-D-tryptophan bound to… | x-ray diffraction | E, F, G | — | — |
| 1GHB | A second active site in chymotrypsin? the X-ray crystal structure of N-acetyl-D-tryptophan bound to… | x-ray diffraction | E, F, G | — | — |
| 1GL0 | structure of the complex between bovine alpha-chymotrypsin and PMP-D2v, an inhibitor from the… | x-ray diffraction | E | — | — |
| 1GL0 | Structure of the complex between bovine alpha-chymotrypsin and pmp-D2V, an inhibitor from the… | x-ray diffraction | E | — | — |
| 1GL1 | structure of the complex between bovine alpha-chymotrypsin and PMP-C, an inhibitor from the insect… | x-ray diffraction | A, B, C | — | — |
| 1GL1 | Structure of the complex between bovine alpha-chymotrypsin and pmp-C, an inhibitor from the insect… | x-ray diffraction | A, B, C | — | — |
| 1GMC | The X-ray crystal structure of the tetrahedral intermediate of gamma-chymotrypsin in hexane | x-ray diffraction | E, F, G | — | — |
| 1GMC | The X-ray crystal structure of the tetrahedral intermediate of gamma- chymotrypsin in hexane | x-ray diffraction | E, F, G | — | — |
| 1GMD | X-ray crystal structure of gamma-chymotrypsin in hexane | x-ray diffraction | E, F, G | — | — |
| 1GMD | X-ray crystal structure of gamma-chymotrypsin in hexane | x-ray diffraction | E, F, G | — | — |
| 1GMH | Refined crystal structure of "aged" and "non-aged" organophosphoryl conjugates of gamma-chymotrypsin | x-ray diffraction | E, F, G | — | — |
| 1GMH | Refined crystal structure of "aged" and "non-aged" organophosphoryl conjugates of gamma-chymotrypsin | x-ray diffraction | E, F, G | — | — |
| 1HJA | Lys 18 variant of turkey ovomucoid inhibitor third domain complexed with alpha-chymotrypsin | x-ray diffraction | A, B, C | — | — |
| 1HJA | Lys 18 variant of turkey ovomucoid inhibitor third domain complexed with alpha-chymotrypsin | x-ray diffraction | A, B, C | — | — |
| 1K2I | Crystal Structure of Gamma-Chymotrypsin in Complex with 7-Hydroxycoumarin | x-ray diffraction | 1 | — | — |
| 1K2I | Crystal structure of gamma-chymotrypsin in complex with 7- hydroxycoumarin | x-ray diffraction | 1 | — | — |
| 1MTN | Bovine alpha-CHYMOTRYPSIN:BPTI crystallization | x-ray diffraction | A, B, C, E, F, G | — | — |
| 1MTN | Bovine alpha-CHYMOTRYPSIN:BPTI crystallization | x-ray diffraction | A, B, C, E, F, G | — | — |
| 1N8O | Crystal structure of a complex between bovine chymotrypsin and ecotin | x-ray diffraction | A, B, C | — | — |
| 1N8O | Crystal structure of a complex between bovine chymotrypsin and ecotin | x-ray diffraction | A, B, C | — | — |
| 1OXG | Crystal structure of a complex formed between organic solvent treated bovine alpha-chymotrypsin and… | x-ray diffraction | A, B | — | — |
| 1OXG | Crystal structure of a complex formed between organic solvent treated bovine alpha-chymotrypsin and… | x-ray diffraction | A, B | — | — |
| 1P2M | Structural consequences of accommodation of four non-cognate amino-acid residues in the S1 pocket… | x-ray diffraction | A, C | — | — |
| 1P2M | Structural consequences of accommodation of four non-cognate amino- acid residues in the S1 pocket… | x-ray diffraction | A, C | — | — |
| 1P2N | Structural consequences of accommodation of four non-cognate amino-acid residues in the S1 pocket… | x-ray diffraction | A, C | — | — |
| 1P2N | Structural consequences of accommodation of four non-cognate amino- acid residues in the S1 pocket… | x-ray diffraction | A, C | — | — |
| 1P2O | Structural consequences of accommodation of four non-cognate amino-acid residues in the S1 pocket… | x-ray diffraction | A, C | — | — |
| 1P2O | Structural consequences of accommodation of four non-cognate amino- acid residues in the S1 pocket… | x-ray diffraction | A, C | — | — |
98 records more on the page itself.
Ligands
- SO4 · Sulfate ion · in 23 records
- IOD · Iodide ion · in 18 records
- LPF · 1,1,1-trifluoro-3-((N-acetyl)-L-leucylamido)-4-phenyl-butan-2-one(n-acetyl-L-leucyl-L-phenylalanyl trifluoromethyl ketone) · in 2 records
- APF · 1,1,1-trifluoro-3-acetamido-4-phenyl butan-2-one(n-acetyl-L-phenylalanyl trifluoromethyl ketone) · in 1 record
- PBA · Phenylethane boronic acid · in 1 record
Experiment against prediction
- 2GCT chain C against the predicted model P00766: TM-score 0.99, RMSD 0.33 Å
- 2GCT chain C against the predicted model P00766: TM-score 0.99, RMSD 0.33 Å
- 1VGC chain C against the predicted model P00766: TM-score 0.99, RMSD 0.33 Å
- 1VGC chain C against the predicted model P00766: TM-score 0.99, RMSD 0.33 Å
- 3GCT chain G against the predicted model P00766: TM-score 0.99, RMSD 0.34 Å
- 3GCT chain G against the predicted model P00766: TM-score 0.99, RMSD 0.34 Å
- 1GCT chain C against the predicted model P00766: TM-score 0.99, RMSD 0.35 Å
- 1GCT chain C against the predicted model P00766: TM-score 0.99, RMSD 0.35 Å
- 5J4S chain A against the predicted model P00766: TM-score 0.99, RMSD 0.83 Å
- 5J4S chain A against the predicted model P00766: TM-score 0.99, RMSD 0.83 Å
Elsewhere
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