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Ligand · LPF

LPF · 1,1,1-trifluoro-3-((N-acetyl)-L-leucylamido)-4-phenyl-butan-2-one(n-acetyl-L-leucyl-L-phenylalanyl trifluoromethyl ketone)

LPF, 1,1,1-trifluoro-3-((N-acetyl)-L-leucylamido)-4-phenyl-butan-2-one(n-acetyl-L-leucyl-L-phenylalanyl trifluoromethyl ketone) (C18 H23 F3 N2 O3, 372.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
LPF
Formula
C18 H23 F3 N2 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

LPF in 2 structures; the first of them:

  • 7GCH · Structure of chymotrypsin-*trifluoromethyl ketone inhibitor complexes. comparison of… · LPF G246 · binds PHE41, CYS42, HIS57, ILE99, SER190, CYS191, MET192, GLY193 and 6 more
  • 7GCH · Structure of chymotrypsin-*trifluoromethyl ketone inhibitor complexes. comparison of… · LPF G246 · binds PHE41, CYS42, HIS57, ILE99, SER190, CYS191, MET192, GLY193 and 6 more

Residues it binds most

SER 2, CYS 2, GLY 2, ASP 2, HIS 2, ILE 2, MET 2, PHE 2, TRP 2 (residue and the binding sites it lines).

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