UniProt P00579
RNA polymerase sigma factor RpoD (P00579)
RNA polymerase sigma factor RpoD (UniProt P00579): 106 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P00579
- Protein
- RNA polymerase sigma factor RpoD
- Experimental structures
- 106
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 23 · 4 records with a druggable one
Structures
107 records of P00579 in the MolNFT archive: 106 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1SIG | Crystal structure of a SIGMA70 subunit fragment from escherichia COLI RNA polymerase | x-ray diffraction | A | — | — |
| 1SIG | Crystal structure of a SIGMA70 subunit fragment from escherichia COLI RNA polymerase | x-ray diffraction | A | — | — |
| 1TLH | T4 AsiA bound to sigma70 region 4 | solution nmr | B | — | — |
| 1TLH | T4 asia bound to SIGMA70 region 4 | solution nmr | B | — | — |
| 2P7V | Crystal structure of the Escherichia coli regulator of sigma 70, Rsd, in complex with sigma 70… | x-ray diffraction | B | — | — |
| 2P7V | Crystal structure of the escherichia COLI regulator of sigma 70, rsd, in complex with sigma 70… | x-ray diffraction | B | — | — |
| 3IYD | Three-dimensional EM structure of an intact activator-dependent transcription initiation complex | electron microscopy | F | — | — |
| 3IYD | Three-dimensional EM structure of an intact activator-dependent transcription initiation complex | electron microscopy | F | — | — |
| 3T72 | PhoB(E)-Sigma70(4)-(RNAP-Betha-flap-tip-helix)-DNA Transcription Activation Sub-Complex | x-ray diffraction | o, q | — | — |
| 3T72 | PHOB(E)-SIGMA70(4)-(rnap-betha-flap-tip-helix)-DNA transcription activation sub-complex | x-ray diffraction | o, q | — | — |
| 4JK1 | X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with Guanosine… | x-ray diffraction | X, Y | — | — |
| 4JK1 | X-ray crystal structure of escherichia COLI SIGMA70 holoenzyme in complex with guanosine… | x-ray diffraction | X, Y | — | — |
| 4JK2 | X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with guanosine… | x-ray diffraction | X, Y | — | — |
| 4JK2 | X-ray crystal structure of escherichia COLI SIGMA70 holoenzyme in complex with guanosine… | x-ray diffraction | X, Y | — | — |
| 4JKR | Crystal Structure of E. coli RNA Polymerase in complex with ppGpp | x-ray diffraction | F, L | — | — |
| 4JKR | Crystal structure of E. COLI RNA polymerase in complex with ppgpp | x-ray diffraction | F, L | — | — |
| 4KMU | X-ray crystal structure of the Escherichia coli RNA polymerase in complex with Rifampin | x-ray diffraction | X, Y | — | — |
| 4KMU | X-ray crystal structure of the escherichia COLI RNA polymerase in complex with rifampin | x-ray diffraction | X, Y | — | — |
| 4KN4 | X-ray crystal structure of the Escherichia coli RNA polymerase in complex with… | x-ray diffraction | X, Y | — | — |
| 4KN4 | X-ray crystal structure of the escherichia COLI RNA polymerase in complex with… | x-ray diffraction | X, Y | — | — |
| 4KN7 | X-ray crystal structure of the Escherichia coli RNA polymerase in complex with… | x-ray diffraction | X, Y | — | — |
| 4KN7 | X-ray crystal structure of the escherichia COLI RNA polymerase in complex with… | x-ray diffraction | X, Y | — | — |
| 4LJZ | Crystal Structure Analysis of the E.coli holoenzyme | x-ray diffraction | F, L | — | — |
| 4LJZ | Crystal structure analysis of the E.COLI holoenzyme | x-ray diffraction | F, L | — | — |
| 4LK0 | Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex | x-ray diffraction | F, L | — | — |
| 4LK0 | Crystal structure analysis of the E.COLI HOLOENZYME/T7 GP2 complex | x-ray diffraction | F, L | — | — |
| 4LK1 | Crystal Structure Analysis of the E.coli holoenzyme | x-ray diffraction | F, L | — | — |
| 4LK1 | Crystal structure analysis of the E.COLI holoenzyme | x-ray diffraction | F, L | — | — |
| 4LLG | Crystal Structure Analysis of the E.coli holoenzyme/Gp2 complex | x-ray diffraction | F, L | — | — |
| 4LLG | Crystal structure analysis of the E.COLI HOLOENZYME/GP2 complex | x-ray diffraction | F, L | — | — |
| 4MEX | Crystal structure of Escherichia coli RNA polymerase in complex with salinamide A | x-ray diffraction | F, L | — | — |
| 4MEX | Crystal structure of escherichia COLI RNA polymerase in complex with salinamide a | x-ray diffraction | F, L | — | — |
| 4MEY | Crystal structure of Escherichia coli RNA polymerase holoenzyme | x-ray diffraction | F, L | — | — |
| 4MEY | Crystal structure of escherichia COLI RNA polymerase holoenzyme | x-ray diffraction | F, L | — | — |
| 4XSX | Crystal structure of CBR 703 bound to Escherichia coli RNA polymerase holoenzyme | x-ray diffraction | F, L | — | — |
| 4XSX | Crystal structure of cbr 703 bound to escherichia COLI RNA polymerase holoenzyme | x-ray diffraction | F, L | — | — |
| 4XSY | Crystal structure of cbr 9379 bound to escherichia COLI RNA polymerase holoenzyme | x-ray diffraction | F, L | — | — |
| 4XSZ | Crystal structure of CBR 9393 bound to Escherichia coli RNA polymerase holoenzyme | x-ray diffraction | F, L | — | — |
| 4XSZ | Crystal structure of cbr 9393 bound to escherichia COLI RNA polymerase holoenzyme | x-ray diffraction | F, L | — | — |
| 4YFK | Escherichia coli RNA polymerase in complex with squaramide compound 8. | x-ray diffraction | F, L | — | — |
| 4YFK | Escherichia COLI RNA polymerase in complex with squaramide compound 8. | x-ray diffraction | F, L | — | — |
| 4YFN | Escherichia coli RNA polymerase in complex with squaramide compound 14… | x-ray diffraction | F, L | — | — |
| 4YFN | Escherichia COLI RNA polymerase in complex with squaramide compound 14… | x-ray diffraction | F, L | — | — |
| 4YFX | Escherichia coli RNA polymerase in complex with Myxopyronin B | x-ray diffraction | F, L | — | — |
| 4YFX | Escherichia COLI RNA polymerase in complex with myxopyronin B | x-ray diffraction | F, L | — | — |
| 4YG2 | X-ray crystal structur of Escherichia coli RNA polymerase sigma70 holoenzyme | x-ray diffraction | F, L | — | — |
| 4YG2 | X-ray crystal structur of escherichia COLI RNA polymerase SIGMA70 holoenzyme | x-ray diffraction | F, L | — | — |
| 4YLN | E. coli Transcription Initiation Complex - 17-bp spacer and 4-nt RNA | x-ray diffraction | F, L, R | — | — |
| 4YLN | E. COLI transcription initiation complex - 17-bp spacer and 4-nt RNA | x-ray diffraction | F, L, R | — | — |
| 4YLO | E. coli Transcription Initiation Complex - 16-bp spacer and 4-nt RNA | x-ray diffraction | F, L, R | — | — |
| 4YLO | E. COLI transcription initiation complex - 16-bp spacer and 4-nt RNA | x-ray diffraction | F, L, R | — | — |
| 4YLP | E. coli Transcription Initiation Complex - 16-bp spacer and 5-nt RNA | x-ray diffraction | F, L, R | — | — |
| 4YLP | E. COLI transcription initiation complex - 16-bp spacer and 5-nt RNA | x-ray diffraction | F, L, R | — | — |
| 4ZH2 | Crystal structure of escherichia COLI RNA polymerase in complex with CBR703 | x-ray diffraction | F, L | — | — |
| 4ZH3 | Crystal structure of Escherichia coli RNA polymerase in complex with CBRH16-Br | x-ray diffraction | F, L | — | 6 (best 0.81) |
| 4ZH3 | Crystal structure of escherichia COLI RNA polymerase in complex with CBRH16-br | x-ray diffraction | F, L | — | — |
| 4ZH4 | Crystal structure of escherichia COLI RNA polymerase in complex with CBRP18 | x-ray diffraction | F, L | — | — |
| 5UAC | Escherichia coli RNA polymerase and Rifampin complex, wild-type | x-ray diffraction | F, L | — | — |
| 5UAC | Escherichia COLI RNA polymerase and rifampin complex, wild-type | x-ray diffraction | F, L | — | — |
| 5UAG | Escherichia coli RNA polymerase mutant - RpoB D516V | x-ray diffraction | F, L | — | — |
47 records more on the page itself.
Ligands
Experiment against prediction
- 4XSY chain F against the predicted model P00579: TM-score 0.95, RMSD 1.81 Å
- 4XSZ chain F against the predicted model P00579: TM-score 0.95, RMSD 1.86 Å
- 4XSZ chain F against the predicted model P00579: TM-score 0.95, RMSD 1.86 Å
- 4MEX chain F against the predicted model P00579: TM-score 0.95, RMSD 1.84 Å
- 4MEX chain F against the predicted model P00579: TM-score 0.95, RMSD 1.84 Å
- 5UAC chain L against the predicted model P00579: TM-score 0.95, RMSD 1.91 Å
- 5UAC chain L against the predicted model P00579: TM-score 0.95, RMSD 1.91 Å
- 4YFK chain F against the predicted model P00579: TM-score 0.95, RMSD 1.94 Å
- 4YFK chain F against the predicted model P00579: TM-score 0.95, RMSD 1.94 Å
- 4XSX chain F against the predicted model P00579: TM-score 0.94, RMSD 1.92 Å
Elsewhere
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