UniProt P00371
D-amino-acid oxidase (P00371)
D-amino-acid oxidase (UniProt P00371), EC 1.4.3.3: 25 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 32 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P00371
- Protein
- D-amino-acid oxidase
- EC
- 1.4.3.3
- Experimental structures
- 25
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 32 · 3 records with a druggable one
Structures
26 records of P00371 in the MolNFT archive: 25 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AN9 | D-amino acid oxidase complex with O-aminobenzoate | x-ray diffraction | A, B | — | — |
| 1AN9 | D-amino acid oxidase complex with O-aminobenzoate | x-ray diffraction | A, B | — | — |
| 1DAO | Covalent adduct of D-amino acid oxidase from pig kidney with 3-methyl-2-oxo-valeric acid | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1DAO | Covalent adduct of D-amino acid oxidase from pig kidney with 3-methyl-2-oxo-valeric acid | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1DDO | Reduced D-amino acid oxidase from pig kidney in complex with imino-TRP | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1DDO | Reduced D-amino acid oxidase from pig kidney in complex with imino-TRP | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1EVI | Three-dimensional structure of the purple intermediate of porcine kidney D-amino acid oxidase | x-ray diffraction | A, B | — | — |
| 1EVI | Three-dimensional structure of the purple intermediate of porcine kidney D-amino acid oxidase | x-ray diffraction | A, B | — | — |
| 1KIF | D-amino acid oxidase from pig kidney | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1KIF | D-amino acid oxidase from pig kidney | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1VE9 | Porcine kidney D-amino acid oxidase | x-ray diffraction | A, B | — | — |
| 1VE9 | Porcine kidney D-amino acid oxidase | x-ray diffraction | A, B | — | — |
| 3WGT | Crystal structure of D-amino acid oxidase mutant | x-ray diffraction | A, B | — | — |
| 3WGT | Crystal structure of D-amino acid oxidase mutant | x-ray diffraction | A, B | — | — |
| 4YJD | Crystal structure of DAAO(Y228L/R283G) variant (apo form) | x-ray diffraction | A, B | — | — |
| 4YJD | Crystal structure of DAAO(Y228L/R283G) variant (apo form) | x-ray diffraction | A, B | — | — |
| 4YJF | Crystal structure of DAAO(Y228L/R283G) variant (S-methylbenzylamine binding form) | x-ray diffraction | A, B | — | — |
| 4YJF | Crystal structure of DAAO(Y228L/R283G) variant (S-methylbenzylamine binding form) | x-ray diffraction | A, B | — | — |
| 4YJG | Crystal structure of DAAO(Y228L/R283G) variant (R-3-amino 1-phenylbutane binding form) | x-ray diffraction | A, B | 4DD, FAD, SO4 | 9 (best 0.84) |
| 4YJG | Crystal structure of DAAO(Y228L/R283G) variant (R-3-amino 1- phenylbutane binding form) | x-ray diffraction | A, B | — | — |
| 4YJH | Crystal structure of DAAO(Y228L/R283G) variant (R-2-phenylpyrrolidine binding form) | x-ray diffraction | A, B | — | — |
| 4YJH | Crystal structure of DAAO(Y228L/R283G) variant (R-2-phenylpyrrolidine binding form) | x-ray diffraction | A, B | — | — |
| 5WWV | Crystal structure of porcine kidney D-amino acid oxidase mutant (I230A/R283G) | x-ray diffraction | A, B, C, D, E, F, G, H | FAD, 7V3, SO4 | — |
| 5WX2 | Crystal structure of porcine kidney D-amino acid oxidase mutant (I230A/R283G) | x-ray diffraction | A, B, C, D, E, F, G, H | FAD, SO4 | 20 (best 0.89) |
| 5WX2 | Crystal structure of porcine kidney D-amino acid oxidase mutant (I230A/R283G) | x-ray diffraction | A, B, C, D, E, F, G, H | FAD, SO4 | — |
| P00371 | AlphaFold monomer V2.0 prediction for D-amino-acid oxidase (P00371) | predicted | A | — | 3 (best 0.81) |
Ligands
Experiment against prediction
- 4YJF chain A against the predicted model P00371: TM-score 1.00, RMSD 0.35 Å
- 4YJF chain A against the predicted model P00371: TM-score 1.00, RMSD 0.35 Å
- 3WGT chain A against the predicted model P00371: TM-score 1.00, RMSD 0.36 Å
- 3WGT chain A against the predicted model P00371: TM-score 1.00, RMSD 0.36 Å
- 4YJG chain A against the predicted model P00371: TM-score 1.00, RMSD 0.35 Å
- 4YJG chain A against the predicted model P00371: TM-score 1.00, RMSD 0.35 Å
- 4YJF chain B against the predicted model P00371: TM-score 1.00, RMSD 0.34 Å
- 4YJF chain B against the predicted model P00371: TM-score 1.00, RMSD 0.34 Å
- 3WGT chain B against the predicted model P00371: TM-score 1.00, RMSD 0.34 Å
- 3WGT chain B against the predicted model P00371: TM-score 1.00, RMSD 0.34 Å
Elsewhere
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