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Ligand · DTR

DTR · D-tryptophan

DTR, D-tryptophan (C11 H12 N2 O2, 204.2 g/mol), in the MolNFT structures on GenesisL1: bound in 11 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
DTR
Formula
C11 H12 N2 O2
Class
ligand
Structures
11
PDB entries
6

Binding sites

DTR in 11 structures; the first of them:

  • 1DDO · Reduced D-amino acid oxidase from pig kidney in complex with imino-TRP · DTR E350 · binds ARG2, VAL3, VAL4, ASP31, LYS33, GLY173, GLY174, ALA175
  • 1TKF · Streptomyces griseus aminopeptidase complexed with D-tryptophan · DTR A913 · binds HIS85, ASP97, GLU131, GLU132, ASP160, MET161, TYR172, GLU196 and 6 more
  • 2V7K · PrnB D-tryptophan complex · DTR A1361 · binds LEU114, LEU140, VAL144, PHE201, TYR209, PRO222, GLY223, ALA224 and 2 more
  • 4NAP · Crystal structure of a trap periplasmic solute binding protein from Desulfovibrio… · DTR A401 · binds PHE40, PRO41, THR45, PHE46, PRO47, SER97, TYR100, SER150 and 8 more
  • 5E5G · 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with D-tryptophan bound in the… · DTR A503 · binds ILE7, PHE91, MET92, ARG171, ALA174, ASN175, ALA178, TRP3 and 7 more
  • 8AD7 · Flavin-dependent tryptophan 6-halogenase Thal in complex with D-Trp · DTR A608 · binds VAL52, PRO53, LYS79, VAL82, HIS110, PRO111, PHE112, GLY113 and 8 more
  • 1DDO · Reduced D-amino acid oxidase from pig kidney in complex with imino-TRP · DTR E350 · binds ARG2, VAL3, VAL4, ASP31, LYS33, GLY173, GLY174, ALA175
  • 1TKF · Streptomyces griseus aminopeptidase complexed with D- tryptophan · DTR A913 · binds HIS85, ASP97, GLU131, GLU132, ASP160, MET161, TYR172, GLU196 and 6 more
  • 2V7K · Prnb D-tryptophan complex · DTR A1361 · binds LEU114, LEU140, VAL144, PHE201, TYR209, PRO222, GLY223, ALA224 and 2 more
  • 4NAP · Crystal structure of a trap periplasmic solute binding protein from desulfovibrio… · DTR A401 · binds PHE40, PRO41, THR45, PHE46, PRO47, SER97, TYR100, SER150 and 8 more
  • 5E5G · 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with D-tryptophan bound in the… · DTR A503 · binds ILE7, PHE91, MET92, ARG171, ALA174, ASN175, ALA178, TRP3 and 7 more

Residues it binds most

VAL 23, PHE 17, ALA 16, SER 15, TYR 17, THR 12, PRO 13, ARG 18, ASP 14, LEU 6 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • FAD · Flavin-adenine dinucleotide
  • HEM · Protoporphyrin IX containing Fe
  • ITR · Imino-tryptophan
  • CA · Calcium ion
  • MN · Manganese (II) ion
  • ZN · Zinc ion
  • PO4 · Phosphate ion
  • GOL · Glycerol

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