UniProt P00363
Fumarate reductase flavoprotein subunit (P00363)
Fumarate reductase flavoprotein subunit (UniProt P00363), EC 1.3.5.4: 16 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P00363
- Protein
- Fumarate reductase flavoprotein subunit
- EC
- 1.3.5.4
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 10 · 1 record with a druggable one
Structures
17 records of P00363 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1KF6 | E. coli Quinol-Fumarate Reductase with Bound Inhibitor HQNO | x-ray diffraction | A, M | — | — |
| 1KF6 | E. COLI quinol-fumarate reductase with bound inhibitor hqno | x-ray diffraction | A, M | — | — |
| 1KFY | Quinol-fumarate reductase with quinol inhibitor 2-[1-(4-chloro-phenyl)-ethyl]-4,6-dinitro-phenol | x-ray diffraction | A, M | — | — |
| 1KFY | Quinol-fumarate reductase with quinol inhibitor 2-[1-(4-chloro- phenyl)-ethyl]-4,6-dinitro-phenol | x-ray diffraction | A, M | — | — |
| 1L0V | Quinol-Fumarate Reductase with Menaquinol Molecules | x-ray diffraction | A, M | — | — |
| 1L0V | Quinol-fumarate reductase with menaquinol molecules | x-ray diffraction | A, M | — | — |
| 2B76 | E. COLI quinol fumarate reductase frda E49Q mutation | x-ray diffraction | — | — | |
| 3CIR | E. coli Quinol fumarate reductase FrdA T234A mutation | x-ray diffraction | A, M | — | — |
| 3CIR | E. COLI quinol fumarate reductase frda T234A mutation | x-ray diffraction | A, M | — | — |
| 4KX6 | Plasticity of the qui -binding site of the complex II homolog quinol:fumarate reductase | x-ray diffraction | A, M | — | — |
| 4KX6 | Plasticity of the quinone-binding site of the complex II homolog QUINOL:FUMARATE reductase | x-ray diffraction | A, M | — | — |
| 5VPN | E. coli Quinol fumarate reductase FrdA E245Q mutation | x-ray diffraction | A, E | FAD | 10 (best 0.87) |
| 5VPN | E. COLI quinol fumarate reductase frda E245Q mutation | x-ray diffraction | A, E | FAD | — |
| 6AWF | Escherichia COLI QUINOL:FUMARATE reductase crystallized without dicarboxylate | x-ray diffraction | A, E | FAD, PO4 | — |
| 6B58 | FrdA-SdhE assembly intermediate | x-ray diffraction | A, C | FAD, K | — |
| 6B58 | Frda-sdhe assembly intermediate | x-ray diffraction | A, C | FAD, K | — |
| P00363 | AlphaFold monomer V2.0 prediction for fumarate reductase flavoprotein subunit (P00363) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6AWF chain A against the predicted model P00363: TM-score 0.99, RMSD 0.70 Å
- 6AWF chain E against the predicted model P00363: TM-score 0.99, RMSD 0.66 Å
- 1KF6 chain A against the predicted model P00363: TM-score 0.99, RMSD 0.88 Å
- 1KF6 chain A against the predicted model P00363: TM-score 0.99, RMSD 0.88 Å
- 1KFY chain A against the predicted model P00363: TM-score 0.99, RMSD 0.90 Å
- 1KFY chain A against the predicted model P00363: TM-score 0.99, RMSD 0.90 Å
- 4KX6 chain A against the predicted model P00363: TM-score 0.99, RMSD 0.92 Å
- 4KX6 chain A against the predicted model P00363: TM-score 0.99, RMSD 0.92 Å
- 1L0V chain A against the predicted model P00363: TM-score 0.99, RMSD 0.97 Å
- 1L0V chain A against the predicted model P00363: TM-score 0.99, RMSD 0.97 Å
Elsewhere
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