UniProt P00163
Cytochrome b (P00163)
Cytochrome b (UniProt P00163), EC 7.1.1.8: 25 experimental structures and 1 predicted model on GenesisL1, 12 ligands bound, 43 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P00163
- Protein
- Cytochrome b
- EC
- 7.1.1.8
- Experimental structures
- 25
- Predicted models
- 1
- Ligands
- 12
- Pockets
- 43 · 5 records with a druggable one
Structures
26 records of P00163 in the MolNFT archive: 25 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1KB9 | Yeast cytochrome BC1 complex | x-ray diffraction | C | — | — |
| 1KB9 | Yeast cytochrome BC1 complex | x-ray diffraction | C | — | — |
| 1KYO | Yeast cytochrome BC1 complex with bound substrate cytochrome C | x-ray diffraction | C, N | — | — |
| 1KYO | Yeast cytochrome BC1 complex with bound substrate cytochrome C | x-ray diffraction | C, N | — | — |
| 1P84 | HDBT inhibited Yeast Cytochrome bc1 Complex | x-ray diffraction | C | — | — |
| 1P84 | Hdbt inhibited yeast cytochrome BC1 complex | x-ray diffraction | C | — | — |
| 2IBZ | Yeast Cytochrome BC1 Complex with Stigmatellin | x-ray diffraction | C | — | — |
| 2IBZ | Yeast cytochrome BC1 complex with stigmatellin | x-ray diffraction | C | — | — |
| 3CX5 | Structure of complex III with bound cytochrome c in reduced state and definition of a minimal core… | x-ray diffraction | C, N | — | — |
| 3CX5 | Structure of complex III with bound cytochrome C in reduced state and definition of a minimal core… | x-ray diffraction | C, N | — | — |
| 3CXH | Structure of yeast complex III with isoform-2 cytochrome c bound and definition of a minimal core… | x-ray diffraction | C, N | — | — |
| 3CXH | Structure of yeast complex III with isoform-2 cytochrome C bound and definition of a minimal core… | x-ray diffraction | C, N | — | — |
| 4PD4 | Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of… | x-ray diffraction | C | — | — |
| 4PD4 | Structural analysis of atovaquone-inhibited cytochrome BC1 complex reveals the molecular basis of… | x-ray diffraction | C | — | — |
| 6GIQ | Saccharomyces cerevisiae respiratory supercomplex III2IV | electron microscopy | C, N | 6PH, HEM, 8PE, CN5, UQ6, 7PH | — |
| 6HU9 | III2-IV2 mitochondrial respiratory supercomplex from S. cerevisiae | electron microscopy | C, N | PEF, HEM, UQ6, CDL, PCF | — |
| 6HU9 | III2-IV2 mitochondrial respiratory supercomplex from S. cerevisiae | electron microscopy | C, N | PEF, HEM, UQ6, CDL, PCF | — |
| 6T0B | The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae | electron microscopy | C, N | CDL, PEF, HEM, PCF | 9 (best 0.83) |
| 6T0B | The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae | electron microscopy | C, N | CDL, PEF, HEM, PCF | — |
| 6T15 | The III2-IV(5B)1 respiratory supercomplex from S. cerevisiae | electron microscopy | C, N | PEF, HEM, CDL, PCF | — |
| 6YMX | CIII2/CIV respiratory supercomplex from Saccharomyces cerevisiae | electron microscopy | C, N | 6PH, HEM, 8PE, CN5, UQ6, 9PE | 12 (best 0.85) |
| 6YMX | CIII2/CIV respiratory supercomplex from saccharomyces cerevisiae | electron microscopy | C, N | 6PH, HEM, 8PE, CN5, UQ6, 9PE | — |
| 8E7S | III2IV2 respiratory supercomplex from Saccharomyces cerevisiae with 4 bound UQ6 | electron microscopy | J, j | PEF, CDL, CN5, HEM, UQ6 | 5 (best 0.85) |
| 8EC0 | III2IV respiratory supercomplex from Saccharomyces cerevisiae cardiolipin-lacking mutant | electron microscopy | J, j | PEF, PGT, HEM, UQ6 | 9 (best 0.87) |
| 9ETZ | III2IV respiratory supercomplex from Saccharomyces cerevisiae | electron microscopy | C, N | CDL, HEM, PEF, PCF, UQ6 | 8 (best 0.85) |
| P00163 | AlphaFold monomer V2.0 prediction for cytochrome B (P00163) | predicted | A | — | — |
Ligands
- HEM · Protoporphyrin IX containing Fe · in 11 records
- PEF · Di-palmitoyl-3-sn-phosphatidylethanolamine · in 8 records
- UQ6 · 5-(3,7,11,15,19,23-hexamethyl-tetracosa-2,6,10,14,18, 22-hexaenyl)-2,3-dimethoxy-6-methyl-benzene-1,4-diol · in 8 records
- CDL · Cardiolipin · in 7 records
- PCF · 1,2-diacyl-sn-glycero-3-phoshocholine · in 6 records
- CN5 · (5S,11R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-4,6,10, 12,16-pentaoxa-5,11-diphosphaoctadec-1-yl pentadecanoate · in 4 records
- 6PH · (1R)-2-(phosphonooxy)-1-[(tridecanoyloxy)methyl]ethyl pentadecanoate · in 3 records
- 7PH · (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate · in 3 records
- 8PE · (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate · in 3 records
- 9PE · (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate · in 3 records
- CN3 · (2R,5S,11R,14R)-5,8,11-trihydroxy-2-(nonanoyloxy)-5,11-dioxido-16-oxo-14-[(propanoyloxy)methyl]-4,6,10,12,15-pentaoxa-5,11-diphosphanonadec-1-yl undecanoate · in 3 records
- PGT · (1S)-2-{[{[(2R)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate · in 1 record
Experiment against prediction
- 1KB9 chain C against the predicted model P00163: TM-score 1.00, RMSD 0.24 Å
- 1KB9 chain C against the predicted model P00163: TM-score 1.00, RMSD 0.24 Å
- 2IBZ chain C against the predicted model P00163: TM-score 1.00, RMSD 0.24 Å
- 2IBZ chain C against the predicted model P00163: TM-score 1.00, RMSD 0.24 Å
- 3CX5 chain C against the predicted model P00163: TM-score 1.00, RMSD 0.25 Å
- 3CX5 chain C against the predicted model P00163: TM-score 1.00, RMSD 0.25 Å
- 3CX5 chain N against the predicted model P00163: TM-score 1.00, RMSD 0.26 Å
- 3CX5 chain N against the predicted model P00163: TM-score 1.00, RMSD 0.26 Å
- 3CXH chain N against the predicted model P00163: TM-score 1.00, RMSD 0.27 Å
- 3CXH chain N against the predicted model P00163: TM-score 1.00, RMSD 0.27 Å
Elsewhere
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