UniProt O96693
1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic (O96693)
1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic (UniProt O96693): 18 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 8 pockets. Binding sites, druggability and experiment against…
- UniProt
- O96693
- Protein
- 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 8 · 2 records with a druggable one
Structures
19 records of O96693 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3AU8 | Crystal structure of the ternary complex of an isomerase | x-ray diffraction | A, B | — | — |
| 3AU8 | Crystal structure of the ternary complex of an isomerase | x-ray diffraction | A, B | — | — |
| 3AU9 | Crystal structure of the quaternary complex-1 of an isomerase | x-ray diffraction | A, B | — | — |
| 3AU9 | Crystal structure of the quaternary complex-1 of an isomerase | x-ray diffraction | A, B | — | — |
| 3AUA | Crystal structure of the quaternary complex-2 of an isomerase | x-ray diffraction | A, B | — | — |
| 3AUA | Crystal structure of the quaternary complex-2 of an isomerase | x-ray diffraction | A, B | — | — |
| 3WQQ | Crystal structure of PfDXR complexed with inhibitor-3 | x-ray diffraction | A, B | — | — |
| 3WQQ | Crystal structure of pfdxr complexed with inhibitor-3 | x-ray diffraction | A, B | — | — |
| 3WQR | Crystal structure of pfdxr complexed with inhibitor-12 | x-ray diffraction | A, B | — | — |
| 3WQR | Crystal structure of pfdxr complexed with inhibitor-12 | x-ray diffraction | A, B | — | — |
| 3WQS | Crystal structure of pfdxr complexed with inhibitor-126 | x-ray diffraction | B | — | — |
| 3WQS | Crystal structure of pfdxr complexed with inhibitor-126 | x-ray diffraction | B | — | — |
| 4GAE | Crystal structure of plasmodium dxr in complex with a pyridine-containing inhibitor | x-ray diffraction | A, B | — | — |
| 4GAE | Crystal structure of plasmodium dxr in complex with a pyridine- containing inhibitor | x-ray diffraction | A, B | — | — |
| 4KP7 | Structure of Plasmodium IspC in complex with a beta-thia-isostere derivative of Fosmidomycin | x-ray diffraction | A, B | — | — |
| 4KP7 | Structure of plasmodium ispc in complex with a beta-thia-isostere derivative of fosmidomycin | x-ray diffraction | A, B | — | — |
| 9JOA | PfDXR - Mn2+ - MAMK89 ternary complex | x-ray diffraction | A, B | MN, UW0, CA | 4 (best 0.78) |
| 9JOB | PfDXR - Mn2+ - NADPH - MAMK89 quaternary complex | x-ray diffraction | A, B | NDP, MN, UW0, CA | 4 (best 0.80) |
| O96693 | AlphaFold monomer V2.0 prediction for 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic… | predicted | A | — | — |
Ligands
Experiment against prediction
- 4KP7 chain B against the predicted model O96693: TM-score 1.00, RMSD 0.28 Å
- 4KP7 chain B against the predicted model O96693: TM-score 1.00, RMSD 0.28 Å
- 9JOB chain A against the predicted model O96693: TM-score 1.00, RMSD 0.38 Å
- 4KP7 chain A against the predicted model O96693: TM-score 1.00, RMSD 0.52 Å
- 4KP7 chain A against the predicted model O96693: TM-score 1.00, RMSD 0.52 Å
- 9JOB chain B against the predicted model O96693: TM-score 0.99, RMSD 0.57 Å
- 3WQQ chain B against the predicted model O96693: TM-score 0.99, RMSD 0.65 Å
- 3WQQ chain B against the predicted model O96693: TM-score 0.99, RMSD 0.65 Å
- 9JOA chain B against the predicted model O96693: TM-score 0.99, RMSD 0.68 Å
- 3AU9 chain B against the predicted model O96693: TM-score 0.99, RMSD 0.66 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.