UniProt O95931
Chromobox protein homolog 7 (O95931)
Chromobox protein homolog 7 (UniProt O95931): 13 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O95931
- Protein
- Chromobox protein homolog 7
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 5
Structures
14 records of O95931 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2K1B | Solution NMR structure of the chromo domain of the chromobox protein homolog 7 | solution nmr | A | — | — |
| 2K1B | Solution NMR structure of the chromo domain of the chromobox protein homolog 7 | solution nmr | A | — | — |
| 2L1B | Solution NMR structure of the chromobox protein Cbx7 with H3K27me3 | solution nmr | A | — | — |
| 2L1B | Solution NMR structure of the chromobox protein CBX7 with H3K27ME3 | solution nmr | A | — | — |
| 3GS2 | Ring1B C-terminal domain/Cbx7 Cbox Complex | x-ray diffraction | B, D | — | — |
| 3GS2 | RING1B C-terminal DOMAIN/CBX7 cbox complex | x-ray diffraction | B, D | — | — |
| 4MN3 | Chromodomain antagonists that target the polycomb-group methyllysine reader protein Chromobox… | x-ray diffraction | A | — | — |
| 4MN3 | Chromodomain antagonists that target the polycomb-group methyllysine reader protein chromobox… | x-ray diffraction | A | — | — |
| 5EPJ | Crystal Structure of chromodomain of CBX7 in complex with inhibitor UNC3866 | x-ray diffraction | A | UNX | — |
| 5EPJ | Crystal structure of chromodomain of CBX7 in complex with inhibitor UNC3866 | x-ray diffraction | A | — | — |
| 6V2R | Crystal Structure of chromodomain of CBX7 mutant V13A in complex with inhibitor UNC3866 | x-ray diffraction | A | UNX | — |
| 6V2R | Crystal structure of chromodomain of CBX7 mutant V13A in complex with inhibitor UNC3866 | x-ray diffraction | A | 5R0, UNX | — |
| 8SII | Crystal Structure of CBX7 with compound UNC4976 | x-ray diffraction | A, B | SO4, CA, CL | — |
| O95931 | AlphaFold monomer V2.0 prediction for chromobox protein homolog 7 (O95931) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6V2R chain A against the predicted model O95931: TM-score 0.94, RMSD 0.66 Å
- 6V2R chain A against the predicted model O95931: TM-score 0.94, RMSD 0.66 Å
- 5EPJ chain A against the predicted model O95931: TM-score 0.94, RMSD 0.63 Å
- 5EPJ chain A against the predicted model O95931: TM-score 0.94, RMSD 0.63 Å
- 4MN3 chain A against the predicted model O95931: TM-score 0.92, RMSD 0.77 Å
- 4MN3 chain A against the predicted model O95931: TM-score 0.92, RMSD 0.77 Å
- 8SII chain A against the predicted model O95931: TM-score 0.92, RMSD 0.81 Å
- 8SII chain B against the predicted model O95931: TM-score 0.90, RMSD 1.14 Å
- 2L1B chain A against the predicted model O95931: TM-score 0.84, RMSD 1.24 Å
- 2L1B chain A against the predicted model O95931: TM-score 0.84, RMSD 1.24 Å
Elsewhere
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