UniProt O95750
Fibroblast growth factor 19 (O95750)
Fibroblast growth factor 19 (UniProt O95750): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O95750
- Protein
- Fibroblast growth factor 19
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
9 records of O95750 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PWA | Crystal structure of Fibroblast Growth Factor 19 | x-ray diffraction | A | — | — |
| 1PWA | Crystal structure of fibroblast growth factor 19 | x-ray diffraction | A | — | — |
| 2P23 | Crystal structure of human FGF19 | x-ray diffraction | A, B | — | — |
| 2P23 | Crystal structure of human FGF19 | x-ray diffraction | A, B | — | — |
| 6KTR | Crystal structure of fibroblast growth factor 19 in complex with Fab | x-ray diffraction | C, D | SO4 | 5 (best 0.51) |
| 6KTR | Crystal structure of fibroblast growth factor 19 in complex with Fab | x-ray diffraction | C, D | SO4 | — |
| 6NFJ | Structure of Beta-Klotho in Complex with FGF19 C-terminal peptide | x-ray diffraction | C, F | — | — |
| 6NFJ | Structure of beta-klotho in complex with FGF19 C-terminal peptide | x-ray diffraction | C, F | — | — |
| O95750 | AlphaFold monomer V2.0 prediction for fibroblast growth factor 19 (O95750) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 1PWA chain A against the predicted model O95750: TM-score 0.97, RMSD 0.91 Å
- 1PWA chain A against the predicted model O95750: TM-score 0.97, RMSD 0.91 Å
- 2P23 chain A against the predicted model O95750: TM-score 0.96, RMSD 1.02 Å
- 2P23 chain A against the predicted model O95750: TM-score 0.96, RMSD 1.02 Å
- 2P23 chain B against the predicted model O95750: TM-score 0.96, RMSD 1.03 Å
- 2P23 chain B against the predicted model O95750: TM-score 0.96, RMSD 1.03 Å
- 6KTR chain D against the predicted model O95750: TM-score 0.96, RMSD 1.03 Å
- 6KTR chain D against the predicted model O95750: TM-score 0.96, RMSD 1.03 Å
- 6KTR chain C against the predicted model O95750: TM-score 0.94, RMSD 1.42 Å
- 6KTR chain C against the predicted model O95750: TM-score 0.94, RMSD 1.42 Å
Elsewhere
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