UniProt O95393
Bone morphogenetic protein 10 (O95393)
Bone morphogenetic protein 10 (UniProt O95393): 14 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 33 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O95393
- Protein
- Bone morphogenetic protein 10
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 33 · 6 records with a druggable one
Structures
15 records of O95393 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6SF1 | Bone morphogenetic protein 10 (BMP10) complexed with extracellular domain of activin receptor-like… | x-ray diffraction | B | NI | 1 (best 0.68) |
| 6SF1 | Bone morphogenetic protein 10 (BMP10) complexed with extracellular domain of activin receptor-like… | x-ray diffraction | B | NI | — |
| 6SF3 | Bone morphogenetic protein 10 (BMP10) in complex with extracellular domain of activin receptor-like… | x-ray diffraction | B | — | 3 (best 0.72) |
| 6SF3 | Bone morphogenetic protein 10 (BMP10) in complex with extracellular domain of activin receptor-like… | x-ray diffraction | B | — | — |
| 7POI | Prodomain bound BMP10 crystal form 1 | x-ray diffraction | A, B, C, D | NAG | 4 (best 0.49) |
| 7POI | Prodomain bound BMP10 crystal form 1 | x-ray diffraction | A, B, C, D | NAG | — |
| 7POJ | Prodomain bound BMP10 crystal form 2 | x-ray diffraction | A, B, C, D | NAG | 5 (best 0.53) |
| 7POJ | Prodomain bound BMP10 crystal form 2 | x-ray diffraction | A, B, C, D | NAG | — |
| 7PPA | High resolution structure of bone morphogenetic protein receptor type II (BMPRII) extracellular… | x-ray diffraction | A, B | — | 5 (best 0.55) |
| 7PPA | High resolution structure of bone morphogenetic protein receptor type II (bmprii) extracellular… | x-ray diffraction | A, B | — | — |
| 7PPB | 2.4 angstrom crystal structure of bone morphogenetic protein receptor type II (BMPRII)… | x-ray diffraction | A | — | 1 (best 0.56) |
| 7PPB | 2.4 ångström crystal structure of bone morphogenetic protein receptor type II (bmprii)… | x-ray diffraction | A | — | — |
| 7PPC | Ternary signalling complex of BMP10 bound to ALK1 and BMPRII | x-ray diffraction | A, B, C, D | — | 14 (best 0.72) |
| 7PPC | Ternary signalling complex of BMP10 bound to ALK1 and bmprii | x-ray diffraction | A, B, C, D | — | — |
| O95393 | AlphaFold monomer V2.0 prediction for bone morphogenetic protein 10 (O95393) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7PPA chain A against the predicted model O95393: TM-score 0.97, RMSD 0.70 Å
- 7PPA chain A against the predicted model O95393: TM-score 0.97, RMSD 0.70 Å
- 7PPC chain D against the predicted model O95393: TM-score 0.97, RMSD 0.70 Å
- 7PPC chain D against the predicted model O95393: TM-score 0.97, RMSD 0.70 Å
- 7PPC chain B against the predicted model O95393: TM-score 0.97, RMSD 0.70 Å
- 7PPC chain B against the predicted model O95393: TM-score 0.97, RMSD 0.70 Å
- 6SF3 chain B against the predicted model O95393: TM-score 0.97, RMSD 0.72 Å
- 6SF3 chain B against the predicted model O95393: TM-score 0.97, RMSD 0.72 Å
- 7PPC chain C against the predicted model O95393: TM-score 0.97, RMSD 0.73 Å
- 7PPC chain C against the predicted model O95393: TM-score 0.97, RMSD 0.73 Å
Elsewhere
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